Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17762870 | 0.84 | LSS (0.34) | LMNA | |
| SCHEMBL23806890 | 0.83 | HRH3 (0.36) | HRH3 | |
| SCHEMBL25701277 | 0.81 | HRH3 (0.40) | HRH3SLC6A4 | |
| SCHEMBL15745488 | 0.79 | LSS (0.36) | LMNA | |
| SCHEMBL24509144 | 0.78 | HRH3 (0.37) | HRH3 | |
| SCHEMBL23945564 | 0.77 | HRH3 (0.38) | HRH3 | |
| SCHEMBL24509141 | 0.76 | HRH3 (0.36) | HRH3 | |
| SCHEMBL17995585 | 0.75 | HRH3 (0.43) | HRH3 | |
| SCHEMBL10104075 | 0.75 | HRH3 (0.41) | HRH3SLC6A4 | |
| SCHEMBL25461029 | 0.74 | SLC6A3 (0.32) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022125800-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-06-16 | — | — | WO | disclosed |