Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26228251 | 0.86 | L3MBTL1 (0.37) | EPHX1EPHX2KDM4E | |
| SCHEMBL24607571 | 0.84 | — | — | |
| SCHEMBL23560373 | 0.84 | — | — | |
| SCHEMBL18633184 | 0.81 | L3MBTL1 (0.31) | — | |
| SCHEMBL22794500 | 0.81 | CYP2D6 (0.45) | TSHR | |
| SCHEMBL15113488 | 0.80 | TSHR (0.39) | TSHREPHX1EPHX2KDM4EGAA | |
| SCHEMBL22790803 | 0.77 | TSHR (0.37) | TSHREPHX1EPHX2KDM4EGAA | |
| SCHEMBL26261665 | 0.76 | HRH3 (0.33) | — | |
| SCHEMBL25088928 | 0.74 | CYP1A2 (0.36) | TSHRKDM4EGAAHSD11B1 | |
| SCHEMBL19157875 | 0.74 | TSHR (0.35) | TSHRKDM4EGAAHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022125800-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-06-16 | — | — | WO | disclosed |