Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 14/20 | 0.47 |
| ▸ | BRD2 | P25440 | 8/20 | 0.47 |
| ▸ | BRD3 | Q15059 | 8/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29717155 | 1.00 | BRD4 (0.47) | BRD4BRD2BRD3TP53MEN1 | |
| SCHEMBL24512238 | 0.79 | POLB (0.49) | BRD4BRD2BRD3 | |
| SCHEMBL29717098 | 0.79 | POLB (0.49) | BRD4BRD2BRD3 | |
| SCHEMBL24512477 | 0.78 | L3MBTL1 (0.33) | KMT2A | |
| SCHEMBL30899302 | 0.77 | BRD4 (0.36) | BRD4BRD2BRD3 | |
| SCHEMBL24512240 | 0.76 | CNR1 (0.47) | BRD4BRD2BRD3MEN1KMT2A | |
| SCHEMBL24512215 | 0.74 | CNR1 (0.46) | BRD4BRD2BRD3TP53 | |
| SCHEMBL30899281 | 0.72 | MAOB (0.35) | BRD4BRD2BRD3 | |
| SCHEMBL30899275 | 0.71 | HPGD (0.65) | MEN1KMT2APKM | |
| SCHEMBL24512107 | 0.71 | HPGD (0.65) | MEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022125989-A1 | COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE, DEGENERATIVE AND METABOLIC DISORDERS | SCRIPPS RESEARCH INSTITUTE, THE (US) | 2022-06-16 | — | — | WO | disclosed |