Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HINT1 | P49773 | 5/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 4/20 | 0.37 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.36 |
| ▸ | KRAS | P01116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24512468 | 1.00 | KDM4E (0.48) | KDM4ETAS1R3TAS1R1ALDH1A1MEN1 | |
| SCHEMBL24512723 | 0.92 | KDM4E (0.54) | KDM4ETAS1R3TAS1R1ALDH1A1MEN1 | |
| SCHEMBL24512508 | 0.92 | KDM4E (0.54) | KDM4ETAS1R3TAS1R1ALDH1A1MEN1 | |
| SCHEMBL29664919 | 0.92 | TAS1R3 (0.53) | KDM4ETAS1R3TAS1R1ALDH1A1HINT1 | |
| SCHEMBL29870610 | 0.92 | TAS1R3 (0.53) | KDM4ETAS1R3TAS1R1ALDH1A1HINT1 | |
| SCHEMBL24512507 | 0.92 | TAS1R3 (0.53) | KDM4ETAS1R3TAS1R1ALDH1A1HINT1 | |
| SCHEMBL25107034 | 0.92 | TAS1R3 (0.53) | KDM4ETAS1R3TAS1R1ALDH1A1HINT1 | |
| SCHEMBL25613001 | 0.91 | KDM4E (0.48) | KDM4ETAS1R3TAS1R1ALDH1A1MEN1 | |
| SCHEMBL24181915 | 0.87 | KDM4E (0.56) | KDM4ETAS1R3TAS1R1ALDH1A1MEN1 | |
| SCHEMBL22883219 | 0.87 | TAS1R3 (0.62) | KDM4ETAS1R3TAS1R1HINT1IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022123501-A1 | PROTECTED DEOXYDIDEHYDRO-NUCLEOSIDES | VICTORIA LINK LIMITED (NZ) | 2022-06-16 | — | — | WO | disclosed |