Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24512962 | 0.87 | KDM4E (0.40) | KMT2AMEN1KDM4EALDH1A1MAPK1 | |
| SCHEMBL24512967 | 0.82 | ALDH1A1 (0.40) | KMT2AMEN1KDM4EALDH1A1MAPK1 | |
| SCHEMBL24512718 | 0.81 | KMT2A (0.50) | KMT2AMEN1KDM4EALDH1A1MAPK1 | |
| SCHEMBL4902910 | 0.77 | KMT2A (0.44) | KMT2AMEN1KDM4EALDH1A1MAPK1 | |
| SCHEMBL31372952 | 0.76 | KMT2A (0.51) | KMT2AMEN1KDM4EALDH1A1MAPK1 | |
| SCHEMBL10472779 | 0.76 | KMT2A (0.51) | KMT2AMEN1KDM4EALDH1A1MAPK1 | |
| SCHEMBL22917910 | 0.75 | KMT2A (0.50) | KMT2AMEN1KDM4EALDH1A1MAPK1 | |
| SCHEMBL10474351 | 0.74 | KMT2A (0.49) | KMT2AMEN1 | |
| SCHEMBL10997351 | 0.74 | KMT2A (0.46) | KMT2AMEN1KDM4EALDH1A1MAPK1 | |
| SCHEMBL13652346 | 0.73 | KMT2A (0.54) | KMT2AMEN1KDM4EALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240043446-A1 | ANTHELMINTIC COMPOUNDS COMPRISING A THIENOPYRIDINE STRUCTURE | INTERVET INC. (US) | 2024-02-08 | — | — | US | disclosed |
| EP-4259636-A1 | ANTHELMINTIC COMPOUNDS COMPRISING A THIENOPYRIDINE STRUCTURE | Intervet International B.V. (NL) | 2023-10-18 | — | — | EP | disclosed |
| WO-2022122988-A1 | ANTHELMINTIC COMPOUNDS COMPRISING A THIENOPYRIDINE STRUCTURE | INTERVET INTERNATIONAL B.V. (NL) | 2022-06-16 | — | — | WO | disclosed |
| WO-2022122988-A1 | ANTHELMINTIC COMPOUNDS COMPRISING A THIENOPYRIDINE STRUCTURE | INTERVET INTERNATIONAL B.V. (NL) | 2022-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240043446-A1 | ANTHELMINTIC COMPOUNDS COMPRISING A THIENOPYRIDINE STRUCTURE | DHODH, NISCH, DDT | KMT2A 1736/4885MEN1 4395/4885KDM4E 1389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.