Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PDE9A | O76083 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1096942 | 0.90 | TYMP (0.45) | TYMPKDM4EHPGDTAS1R3TAS1R1 | |
| SCHEMBL24513002 | 0.90 | TYMP (0.45) | TYMPKDM4EHPGDTAS1R3TAS1R1 | |
| SCHEMBL19362152 | 0.90 | TYMP (0.45) | TYMPKDM4EHPGDTAS1R3TAS1R1 | |
| SCHEMBL25630145 | 0.88 | TYMP (0.42) | TYMPKDM4EHPGDTAS1R3TAS1R1 | |
| SCHEMBL22408780 | 0.84 | TYMP (0.36) | TYMPKDM4EHPGD | |
| SCHEMBL22408779 | 0.84 | TYMP (0.36) | TYMPKDM4EHPGD | |
| SCHEMBL31196681 | 0.83 | KDM4E (0.36) | TYMPKDM4E | |
| SCHEMBL24659264 | 0.83 | TYMP (0.35) | TYMPKDM4E | |
| SCHEMBL23263917 | 0.83 | TYMP (0.35) | TYMPKDM4E | |
| SCHEMBL24512769 | 0.82 | TYMP (0.39) | TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022122613-A1 | NOVEL SYNTHESIS OF PHOSPHORODITHIOATE OLIGONUCLEOTIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2022-06-16 | — | — | WO | disclosed |