Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23263917 | 1.00 | TYMP (0.35) | TYMPKDM4E | |
| SCHEMBL22585454 | 0.91 | TYMP (0.38) | TYMP | |
| SCHEMBL24659263 | 0.91 | TYMP (0.38) | TYMP | |
| SCHEMBL22556255 | 0.87 | TYMP (0.34) | TYMP | |
| SCHEMBL22585590 | 0.87 | TYMP (0.34) | TYMP | |
| SCHEMBL24659260 | 0.87 | TYMP (0.34) | TYMP | |
| SCHEMBL22556250 | 0.87 | TYMP (0.34) | TYMP | |
| SCHEMBL24658930 | 0.87 | TYMP (0.34) | TYMP | |
| SCHEMBL22585429 | 0.87 | TYMP (0.34) | TYMP | |
| SCHEMBL30144743 | 0.87 | TYMP (0.34) | TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002762-A1 | OLIGONUCLEOTIDES COMPRISING A PHOSPHORODITHIOATE INTERNUCLEOSIDE LINKAGE | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2023-01-05 | — | — | US | disclosed |
| EP-4092117-A1 | GAPMER OLIGONUCLEOTIDES COMPRISING A PHOSPHORODITHIOATE INTERNUCLEOSIDE LINKAGE | Roche Innovation Center Copenhagen A/S (DK) | 2022-11-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002762-A1 | OLIGONUCLEOTIDES COMPRISING A PHOSPHORODITHIOATE INTERNUCLEOSIDE LINKAGE | DUT, TYMP, TYMS | TYMP 2/4885KDM4E 4214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.