Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24513172 | 0.78 | KDM4E (0.60) | KDM4ESMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL12289816 | 0.78 | KDM4E (1.00) | KDM4ESMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL2423535 | 0.77 | KDM4E (0.68) | KDM4ESMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL24513188 | 0.73 | RAB9A (0.57) | KDM4ESMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL30282194 | 0.73 | SMN1; SMN2 (0.66) | KDM4ESMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL16432493 | 0.73 | SMN1; SMN2 (0.66) | KDM4ESMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL637433 | 0.72 | KDM4E (0.57) | KDM4ESMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL24513184 | 0.72 | KDM4E (0.64) | KDM4ESMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL13317085 | 0.72 | KDM4E (0.60) | KDM4ESMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL23903089 | 0.72 | SMN1; SMN2 (0.78) | KDM4ESMN1; SMN2LMNARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022122682-A2 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-06-16 | — | — | WO | disclosed |