SCHEMBL24514929

SCHEMBL24514929

C[C@@H](Br)S[C@H](C)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.40
KMT2A Q03164 3/20 0.40
ALDH1A1 P00352 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
TRPA1 O75762 1/20 0.38
MEN1 O00255 2/20 0.38
HBB P68871 1/20 0.38
DAO P14920 1/20 0.38
ADRA2A P08913 1/20 0.37
ADRA2C P18825 1/20 0.37
CYP2D6 P10635 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
LMNA P02545 1/20 0.37
HIF1A Q16665 1/20 0.37
KDM4E B2RXH2 1/20 0.37
CYP3A4 P08684 1/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL577805 0.85 ALDH1A1 (0.46) TAAR1KMT2AALDH1A1L3MBTL1MEN1
SCHEMBL10297589 0.80 ALDH1A1 (0.43) TAAR1KMT2AALDH1A1L3MBTL1MEN1
SCHEMBL28313130 0.76 KMT2A (0.40) TAAR1KMT2AALDH1A1L3MBTL1MEN1
SCHEMBL1462233 0.76 TSHR (0.46) TAAR1KMT2AALDH1A1L3MBTL1MEN1
SCHEMBL20854763 0.76 ALDH1A1 (0.50) KMT2AALDH1A1L3MBTL1MEN1HBB
Bromide SCHEMBL20854776 0.74 ALDH1A1 (0.48) KMT2AALDH1A1L3MBTL1MEN1HBB
SCHEMBL775627 0.74 KMT2A (0.45) TAAR1KMT2AALDH1A1L3MBTL1ADRA2A
SCHEMBL20809867 0.72 KMT2A (0.44) TAAR1KMT2AALDH1A1L3MBTL1ADRA2A
SCHEMBL14535430 0.72 KMT2A (0.44) TAAR1KMT2AALDH1A1L3MBTL1ADRA2A
SCHEMBL1145689 0.72 KMT2A (0.44) TAAR1KMT2AALDH1A1L3MBTL1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022124516-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG Display Co.,Ltd. (KR) 2022-06-16 WO disclosed