Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 14/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2451868 | 1.00 | ADRB2 (0.55) | ADRB2CHRM3ADRB3 | |
| SCHEMBL5037512 | 0.92 | ADRB2 (0.56) | ADRB2ADRB3 | |
| SCHEMBL5037510 | 0.92 | ADRB2 (0.56) | ADRB2ADRB3 | |
| SCHEMBL2959041 | 0.89 | ADRB2 (0.59) | ADRB2CHRM3ADRB3 | |
| SCHEMBL2958560 | 0.89 | ADRB2 (0.59) | ADRB2CHRM3ADRB3 | |
| SCHEMBL2454533 | 0.89 | ADRB2 (0.57) | ADRB2ADRB3 | |
| SCHEMBL2454530 | 0.89 | ADRB2 (0.57) | ADRB2ADRB3 | |
| SCHEMBL5037003 | 0.88 | ADRB2 (0.44) | ADRB2CHRM3ADRB3 | |
| SCHEMBL5037004 | 0.88 | ADRB2 (0.44) | ADRB2CHRM3ADRB3 | |
| SCHEMBL12305650 | 0.87 | ADRB2 (0.57) | ADRB2CHRM3ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013019-B2 | Sulfonamide derivatives for the treatment of diseases | PFIZER INC (US) | 2011-09-06 | — | — | US | disclosed |