SCHEMBL24519713

SCHEMBL24519713

Cc1c(F)c(F)c(CS(=O)(=O)Nc2ccc3c(c2)C(C)OC(O)N3C(C)C)c(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 2/20 0.34
NR3C2 P08235 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24519734 0.87 NR3C2 (0.32) BRD4NR3C2
SCHEMBL20616510 0.80 NR3C2 (0.35) BRD4NR3C2
SCHEMBL20616638 0.77 BRD4 (0.36) BRD4NR3C2
SCHEMBL20616480 0.76 NR3C2 (0.36) BRD4NR3C2
SCHEMBL20616482 0.74 NR3C2 (0.35) BRD4NR3C2
SCHEMBL24519729 0.74
SCHEMBL24519711 0.74
SCHEMBL20616483 0.73 NR3C2 (0.34) BRD4NR3C2
SCHEMBL20616493 0.70 RPS6KA6 (0.33) BRD4NR3C2
SCHEMBL24519737 0.69 BRAF (0.32) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3398940-B1 HIGH STRESS RESISTANT PLANT GROWTH REGULATOR AND PREPARATION METHOD AND USE THEREOF CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2022-06-22 EP disclosed