SCHEMBL20616638

SCHEMBL20616638

Cc1c(F)c(F)c(CS(=O)(=O)Nc2ccc3c(c2)C(C)OC(=O)N3CC(C)C)c(F)c1F

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 3/20 0.36
NR3C2 P08235 1/20 0.35
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20616480 0.89 NR3C2 (0.36) BRD4NR3C2
SCHEMBL20616510 0.88 NR3C2 (0.35) BRD4NR3C2
SCHEMBL20616482 0.88 NR3C2 (0.35) BRD4NR3C2ALDH1A1
SCHEMBL20616483 0.86 NR3C2 (0.34) BRD4NR3C2
SCHEMBL24519718 0.81
SCHEMBL20616493 0.80 RPS6KA6 (0.33) BRD4NR3C2
SCHEMBL19805119 0.79 BRD4 (0.38) BRD4NR3C2
SCHEMBL20616497 0.77 BRD4 (0.33) BRD4NR3C2ALDH1A1
SCHEMBL24519713 0.77 BRD4 (0.34) BRD4NR3C2
SCHEMBL23709378 0.77 PGR (0.31) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3398940-B1 HIGH STRESS RESISTANT PLANT GROWTH REGULATOR AND PREPARATION METHOD AND USE THEREOF CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2022-06-22 EP disclosed
US-11076597-B2 High stress resistant plant growth regulator and preparation method and use thereof CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2021-08-03 US disclosed
US-20190000084-A1 HIGH STRESS RESISTANT PLANT GROWTH REGULATOR AND PREPARATION METHOD AND USE THEREOF SHANGHAI INSTITUTES FOR BIOLOGICAL SCIENCES, CHINESE ACADEMY OF SCIENCES (CN) 2019-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190000084-A1 HIGH STRESS RESISTANT PLANT GROWTH REGULATOR AND PREPARATION METHOD AND USE THEREOF BOLA2; BOLA2B, MYB, PPA1 BRD4 1177/4885NR3C2 154/4885ALDH1A1 3795/4885
US-11076597-B2 High stress resistant plant growth regulator and preparation method and use thereof BOLA2; BOLA2B, MYB, PPA1 BRD4 1177/4885NR3C2 154/4885ALDH1A1 3795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.