Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | GNPAT | O15228 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11896083 | 0.94 | SIRT6 (0.56) | SIRT6SIRT1CHRM2CHRM4CHRM1 | |
| SCHEMBL726302 | 0.94 | SIRT6 (0.56) | SIRT6SIRT1CHRM2CHRM4CHRM1 | |
| Hydrochloric Acid SCHEMBL7347980 | 0.92 | SIRT6 (0.55) | SIRT6SIRT1CHRM2CHRM4CHRM1 | |
| SCHEMBL22592147 | 0.88 | KDM4E (0.42) | SIRT6SIRT1CHRM2CHRM4CHRM1 | |
| SCHEMBL20951590 | 0.86 | FURIN (0.48) | SIRT6SIRT1SIRT5GNPATALDH1A1 | |
| SCHEMBL20951592 | 0.86 | FURIN (0.48) | SIRT6SIRT1SIRT5GNPATALDH1A1 | |
| Acetic Acid SCHEMBL15669859 | 0.85 | FOLH1 (0.40) | SIRT6SIRT1CHRM2CHRM4CHRM1 | |
| SCHEMBL159460 | 0.84 | GNPAT (0.55) | SIRT6SIRT1CHRM2CHRM4CHRM1 | |
| SCHEMBL159459 | 0.84 | GNPAT (0.55) | SIRT6SIRT1CHRM2CHRM4CHRM1 | |
| SCHEMBL159461 | 0.84 | GNPAT (0.55) | SIRT6SIRT1CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129627-A1 | OLIGOMERIC COMPOUNDS BINDING SPECIFICALLY TO PROTEOGLYCANS | PHI PHARMA SA (CH) | 2022-06-23 | — | — | WO | disclosed |
| EP-4015004-A1 | PROTEOGLYCAN SPECIFIC BRANCHED PEPTIDES | Phi Pharma SA (CH) | 2022-06-22 | — | — | EP | disclosed |