SCHEMBL24520175

SCHEMBL24520175

CC1CC(C)CC(CC(N)C(=O)O)C1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.39
GRIK1 P39086 1/20 0.37
SLC1A3 P43003 1/20 0.37
SLC1A2 P43004 1/20 0.37
SLC1A1 P43005 1/20 0.37
GRIK2 Q13002 1/20 0.37
PTGS1 P23219 1/20 0.37
SLC7A11 Q9UPY5 1/20 0.37
ALDH1A1 P00352 1/20 0.36
ALOX15 P16050 1/20 0.36
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36
GRIN1 Q05586 1/20 0.36
GRIN2A Q12879 1/20 0.36
GRIN2B Q13224 1/20 0.36
GRIN2C Q14957 1/20 0.36
GRIN3A Q8TCU5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24548642 1.00 SLC7A5 (0.39) SLC7A5GRIK1SLC1A3SLC1A2SLC1A1
SCHEMBL25660532 0.98 SLC7A5 (0.40) SLC7A5GRIK1SLC1A3SLC1A2SLC1A1
SCHEMBL24520296 0.85 GRIN2D (0.37) SLC7A5GRIK1SLC1A3SLC1A2SLC1A1
SCHEMBL24520248 0.82 ANPEP (0.43) SLC1A3SLC1A2SLC1A1GRIN2DGRIN3B
SCHEMBL24520203 0.82 ANPEP (0.43) SLC1A3SLC1A2SLC1A1GRIN2DGRIN3B
SCHEMBL24520185 0.82 ANPEP (0.43) SLC1A3SLC1A2SLC1A1GRIN2DGRIN3B
SCHEMBL25660400 0.82 EPHX2 (0.36)
SCHEMBL24520238 0.80 ANPEP (0.41) SLC7A5GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL1865821 0.80 ANPEP (0.41) SLC7A5GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL1865818 0.80 ANPEP (0.41) SLC7A5GRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4015529-A1 G PROTEIN PEPTIDOMIMETICS Vrije Universiteit Brussel (BE) 2022-06-22 EP disclosed