SCHEMBL24520296

SCHEMBL24520296

CC1CCC(CC(N)C(=O)O)C1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 5/20 0.37
GRIN3B O60391 5/20 0.37
GRIN1 Q05586 5/20 0.37
GRIN2A Q12879 5/20 0.37
GRIN2B Q13224 5/20 0.37
GRIN2C Q14957 5/20 0.37
GRIN3A Q8TCU5 5/20 0.37
SLC7A5 Q01650 1/20 0.36
SLC1A3 P43003 3/20 0.36
SLC1A2 P43004 3/20 0.36
SLC1A1 P43005 3/20 0.36
EPHX1 P07099 1/20 0.36
GRIK1 P39086 1/20 0.35
GRIK2 Q13002 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24520248 0.89 ANPEP (0.43) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL24520203 0.89 ANPEP (0.43) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL24520185 0.89 ANPEP (0.43) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1865818 0.89 ANPEP (0.41) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL24520238 0.89 ANPEP (0.41) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1865821 0.89 ANPEP (0.41) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL25660532 0.86 SLC7A5 (0.40) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL24520175 0.85 SLC7A5 (0.39) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL24548642 0.85 SLC7A5 (0.39) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL2380451 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4015529-A1 G PROTEIN PEPTIDOMIMETICS Vrije Universiteit Brussel (BE) 2022-06-22 EP disclosed