Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 6/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.38 |
| ▸ | MGLL | Q99685 | 4/20 | 0.38 |
| ▸ | FAAH | O00519 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18786061 | 0.85 | HPGD (0.39) | PTGS1PTGS2MGLLFAAHHPGD | |
| SCHEMBL17345175 | 0.82 | PTGS1 (0.51) | PTGS1PTGS2MGLLFAAH | |
| SCHEMBL14877935 | 0.80 | PTGS1 (0.57) | PTGS1PTGS2MGLLFAAHMEN1 | |
| SCHEMBL18786134 | 0.79 | TSHR (0.40) | PTGS1PTGS2MGLLFAAHHPGD | |
| SCHEMBL18389705 | 0.79 | PTGS1 (0.41) | PTGS1PTGS2MGLLFAAHHPGD | |
| SCHEMBL17345169 | 0.77 | AKT1 (0.33) | PTGS1PTGS2HPGDAKT1SMN1; SMN2 | |
| SCHEMBL16120761 | 0.77 | PTGS1 (0.46) | PTGS1PTGS2MGLLFAAHHPGD | |
| SCHEMBL22455884 | 0.76 | AKT1 (0.33) | PTGS1PTGS2HPGDAKT1ALDH1A1 | |
| SCHEMBL21557778 | 0.76 | AKT1 (0.32) | PTGS1PTGS2AKT1 | |
| SCHEMBL12642012 | 0.76 | PTGS1 (0.54) | PTGS1PTGS2MGLLFAAHHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362100-B1 | HINDERED DISULFIDE DRUG CONJUGATES | GENENTECH INC (US) | 2022-06-22 | — | — | EP | disclosed |