Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17345169 | 0.89 | AKT1 (0.33) | AKT1OPRM1OPRD1OPRK1PTGS1 | |
| SCHEMBL22455884 | 0.86 | AKT1 (0.33) | AKT1OPRM1OPRD1OPRK1PTGS1 | |
| SCHEMBL11982596 | 0.79 | PTGS1 (0.41) | OPRM1OPRD1OPRK1PTGS1PTGS2 | |
| SCHEMBL30199847 | 0.79 | AKT1 (0.33) | AKT1 | |
| SCHEMBL29635323 | 0.79 | AKT1 (0.33) | AKT1OPRM1OPRD1OPRK1 | |
| SCHEMBL18786061 | 0.77 | HPGD (0.39) | AKT1OPRM1OPRD1OPRK1PTGS1 | |
| SCHEMBL23760560 | 0.76 | PTGS1 (0.40) | AKT1OPRM1OPRD1OPRK1PTGS1 | |
| SCHEMBL24520458 | 0.76 | PTGS1 (0.38) | AKT1PTGS1PTGS2 | |
| SCHEMBL18389705 | 0.75 | PTGS1 (0.41) | AKT1OPRM1OPRD1OPRK1PTGS1 | |
| SCHEMBL18786134 | 0.73 | TSHR (0.40) | OPRM1OPRD1OPRK1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3566750-A2 | CONJUGATES COMPRISING CELL-BINDING AGENTS AND CYTOTOXIC AGENTS | ImmunoGen, Inc. (US) | 2019-11-13 | — | — | EP | disclosed |