Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.40 |
| ▸ | DHPS | P49366 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13743097 | 0.80 | CES1 (0.38) | MEN1KMT2AALDH1A1TSHRLMNA | |
| SCHEMBL28025946 | 0.79 | MEN1 (0.48) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL29076993 | 0.76 | PAOX (0.39) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL28830250 | 0.74 | PAOX (0.38) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL1931586 | 0.73 | MEN1 (0.44) | MEN1KMT2ATSHRDHPSLMNA | |
| SCHEMBL20083871 | 0.71 | CES2 (0.42) | MEN1KMT2AALDH1A1TSHRALOX15 | |
| SCHEMBL1932465 | 0.71 | — | — | |
| SCHEMBL8860277 | 0.71 | MEN1 (0.44) | MEN1KMT2AALDH1A1TSHRALOX15 | |
| SCHEMBL11766649 | 0.70 | CES2 (0.42) | MEN1KMT2AALDH1A1TSHRALOX15 | |
| SCHEMBL11766652 | 0.70 | CES2 (0.42) | MEN1KMT2AALDH1A1TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3116509-B1 | A NEW CLASS OF MU-OPIOID RECEPTOR AGONISTS | UNIV COLUMBIA (US) | 2022-06-22 | — | — | EP | disclosed |