SCHEMBL24521063

SCHEMBL24521063

N#Cc1ccc(-c2cccc3c2-c2cc(-c4ccc(-c5ccc(-c6cc(-c7ccccc7)cc(-c7ccccc7)n6)cc5)cc4)c4ccccc4c2C3)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 4/20 0.47
GABRA1 P14867 1/20 0.41
GABRG2 P18507 1/20 0.41
GABRB3 P28472 1/20 0.41
GABRA5 P31644 1/20 0.41
GABRA3 P34903 1/20 0.41
ABCG2 Q9UNQ0 2/20 0.39
ABCB1 P08183 1/20 0.39
SQOR Q9Y6N5 4/20 0.37
HRH4 Q9H3N8 1/20 0.37
ALDH1A3 P47895 1/20 0.37
KDM4E B2RXH2 2/20 0.36
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
MAPK1 P28482 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
LAP3 P28838 1/20 0.35
ACP1 P24666 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24521007 0.90 ABCG2 (0.40) MYCGABRA1GABRG2GABRB3GABRA5
SCHEMBL24521132 0.88 KCNH2 (0.42) MYCGABRG2GABRB3GABRA5GABRA3
SCHEMBL24521125 0.88 ABCG2 (0.40) MYCGABRA1GABRG2GABRB3GABRA5
SCHEMBL24521100 0.88 SQOR (0.39) MYCABCG2SQORHRH4LAP3
SCHEMBL24521004 0.84 CYP1A2 (0.38) ABCG2ABCB1SQORHRH4KDM4E
SCHEMBL23841676 0.80 MYC (0.56) MYCGABRA1GABRG2GABRB3GABRA5
SCHEMBL22064683 0.79 MYC (0.59) MYCGABRA1GABRG2GABRB3GABRA5
SCHEMBL24521105 0.78 MEN1 (0.39) KDM4ELMNASMN1; SMN2ADORA2AADORA1
SCHEMBL22987035 0.78 MYC (0.63) MYCGABRA1GABRG2GABRB3GABRA5
SCHEMBL22987245 0.78 MYC (0.63) MYCGABRA1GABRG2GABRB3GABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4015515-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT Materials Co., Ltd. (KR) 2022-06-22 EP disclosed