Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 9/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24521290 | 0.87 | MEN1 (0.41) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL24521172 | 0.83 | ADORA1 (0.34) | TDP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL24521273 | 0.81 | MEN1 (0.40) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL24521092 | 0.80 | ADORA2A (0.37) | TDP2ALDH1A1MAPTHPGDACHE | |
| SCHEMBL24384482 | 0.80 | SMN1; SMN2 (0.39) | TDP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL25945304 | 0.79 | SRD5A2 (0.46) | TDP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL25540898 | 0.79 | MEN1 (0.43) | TDP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL17467363 | 0.78 | MEN1 (0.36) | TDP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL17734263 | 0.78 | TDP2 (0.38) | TDP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL25720786 | 0.78 | TDP2 (0.41) | TDP2MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4015515-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LT Materials Co., Ltd. (KR) | 2022-06-22 | — | — | EP | disclosed |