Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.77 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12390866 | 0.88 | GPR119 (0.78) | GPR119 | |
| SCHEMBL11946818 | 0.87 | GPR119 (1.00) | GPR119 | |
| SCHEMBL11946821 | 0.87 | GPR119 (0.77) | GPR119HRH1HRH3 | |
| SCHEMBL2333408 | 0.87 | GPR119 (0.77) | GPR119 | |
| SCHEMBL11946817 | 0.87 | GPR119 (0.77) | GPR119 | |
| SCHEMBL2331453 | 0.87 | GPR119 (0.77) | GPR119HRH1HRH3 | |
| SCHEMBL2331178 | 0.87 | GPR119 (1.00) | GPR119 | |
| SCHEMBL2334775 | 0.86 | GPR119 (0.74) | GPR119HRH1HRH3 | |
| SCHEMBL12390760 | 0.86 | GPR119 (0.74) | GPR119HRH1HRH3 | |
| SCHEMBL11946829 | 0.86 | GPR119 (0.74) | GPR119HRH1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170864-B1 | PYRIDONE GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2011-09-14 | — | — | EP | claimed |