SCHEMBL24521529

SCHEMBL24521529

CC(C[C@H](C)Oc1ccc(F)cc1Br)Oc1ccc(F)cc1Br

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.46
MAPT P10636 5/20 0.38
GAA P10253 2/20 0.36
MGAM O43451 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
RAB9A P51151 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
LMNA P02545 2/20 0.34
ATM Q13315 1/20 0.34
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
EPAS1 Q99814 1/20 0.33
L3MBTL1 Q9Y468 3/20 0.33
HPGD P15428 1/20 0.33
HTT P42858 2/20 0.32
APLNR P35414 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17404562 1.00 PKM (0.46) PKMMAPTGAAMGAMSI
SCHEMBL17404587 1.00 PKM (0.46) PKMMAPTGAAMGAMSI
SCHEMBL30681168 1.00 PKM (0.46) PKMMAPTGAAMGAMSI
SCHEMBL21574041 1.00 PKM (0.46) PKMMAPTGAAMGAMSI
SCHEMBL17404506 1.00 PKM (0.46) PKMMAPTGAAMGAMSI
SCHEMBL4349038 0.83 PKM (0.46) PKMMAPTGAAMEN1KMT2A
SCHEMBL17008052 0.82 PKM (0.41) PKMMAPTGAAMGAMSI
SCHEMBL21574037 0.82 PKM (0.48) PKMMAPTMEN1KMT2ARAB9A
SCHEMBL17008054 0.82 PKM (0.41) PKMMAPTGAAMGAMSI
SCHEMBL21574039 0.80 CYP1A2 (0.46) MAPTGAAMEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3356430-B1 A POLYMERIZATION PROCESS FOR PRODUCING ETHYLENE BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-22 EP disclosed