Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.56 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 11/20 | 0.53 |
| ▸ | PPARG | P37231 | 8/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | F2R | P25116 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13059390 | 0.88 | TAOK1 (0.58) | MEN1KMT2ATAOK1TAOK3EPHX2 | |
| Hydrochloric Acid SCHEMBL17687150 | 0.86 | TAOK1 (0.57) | MEN1KMT2ATAOK1TAOK3EPHX2 | |
| SCHEMBL27858969 | 0.85 | EPHX2 (0.62) | MEN1KMT2ATAOK1TAOK3EPHX2 | |
| SCHEMBL23135875 | 0.84 | TAOK1 (0.53) | MEN1KMT2AALDH1A1TAOK1TAOK3 | |
| SCHEMBL17687021 | 0.84 | KMT2A (0.56) | MEN1KMT2AALDH1A1TAOK1TAOK3 | |
| SCHEMBL16269072 | 0.83 | KMT2A (0.58) | MEN1KMT2ATAOK1TAOK3EPHX2 | |
| SCHEMBL18438726 | 0.82 | MEN1 (0.57) | MEN1KMT2AALDH1A1TAOK1TAOK3 | |
| SCHEMBL16269091 | 0.82 | MEN1 (0.60) | MEN1KMT2ATAOK1TAOK3EPHX2 | |
| SCHEMBL7505420 | 0.81 | ALDH1A1 (0.74) | MEN1KMT2AALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL3911493 | 0.81 | EPHX2 (0.55) | MEN1KMT2ATAOK1TAOK3EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4015501-A1 | N-BENZYL-ALPHA-AMINOAMIDES AS ANAPHASE-PROMOTING COMPLEX/CYCLOSOME (APC/C) INHIBITORS | Consejo Superior de Investigaciones Científicas (CSIC) (ES) | 2022-06-22 | — | — | EP | disclosed |
| CN-107108467-A | cell necrosis inhibitor | 北京生命科学研究所 | 2017-08-29 | — | — | CN | disclosed |