SCHEMBL24521694

SCHEMBL24521694

Cc1ccccc1-c1cccc(N)c1S

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.54
TDP1 Q9NUW8 1/20 0.54
CD44 P16070 1/20 0.46
ALDH1A1 P00352 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
TSHR P16473 2/20 0.41
PIK3CA P42336 1/20 0.41
DPP4 P27487 1/20 0.40
HSD17B10 Q99714 1/20 0.37
DHFR P00374 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 1/20 0.36
CASP3 P42574 1/20 0.36
RAB9A P51151 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
MYC P01106 1/20 0.36
ALOX15 P16050 1/20 0.36
CASP1 P29466 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3179746 0.84 TSHR (0.45) CYP3A4ALDH1A1TSHRSMN1; SMN2NPC1
SCHEMBL6757361 0.84 ALDH1A1 (0.50) CYP3A4TDP1CD44ALDH1A1L3MBTL1
SCHEMBL15478649 0.82 TSHR (0.43) CYP3A4ALDH1A1TSHRSMN1; SMN2NPC1
SCHEMBL6153524 0.80
SCHEMBL398724 0.80 ALDH1A1 (0.68) CYP3A4TDP1CD44ALDH1A1L3MBTL1
SCHEMBL7939779 0.78 CYP3A4 (0.56) CYP3A4TDP1CD44ALDH1A1L3MBTL1
SCHEMBL3794848 0.78 CD44 (0.62) CYP3A4TDP1CD44ALDH1A1L3MBTL1
SCHEMBL29414659 0.78 CD44 (0.62) CYP3A4TDP1CD44ALDH1A1L3MBTL1
SCHEMBL19752710 0.78 ALDH1A1 (0.65) CYP3A4TDP1CD44ALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL28067548 0.78 ALDH1A1 (0.65) CYP3A4TDP1CD44ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4016656-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND Samsung Electronics Co., Ltd. (KR) 2022-06-22 EP disclosed