Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 11/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.61 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30991652 | 0.94 | SLC22A2 (0.63) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL22482727 | 0.88 | SLC22A2 (0.57) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL24521695 | 0.87 | SLC22A2 (0.63) | SLC22A2 | |
| SCHEMBL20005999 | 0.87 | SLC22A2 (0.56) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL24799803 | 0.87 | SLC22A2 (0.51) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL10283865 | 0.86 | SLC22A2 (0.60) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL20671129 | 0.84 | — | — | |
| SCHEMBL82674 | 0.84 | SLC22A2 (0.63) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL30991648 | 0.84 | SLC22A2 (0.58) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL25141894 | 0.83 | SLC22A2 (0.57) | SLC22A2CYP3A4TMEM97ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3938047-B1 | BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE | GILEAD SCIENCES INC (US) | 2022-06-22 | — | — | EP | disclosed |