Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 18/20 | 0.50 |
| ▸ | ITGB6 | P18564 | 12/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.50 |
| ▸ | ITGB5 | P18084 | 5/20 | 0.45 |
| ▸ | ITGB8 | P26012 | 6/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24521941 | 0.83 | ITGAV (0.46) | ITGAVITGB3ITGB6ITGA2BITGB5 | |
| SCHEMBL24521922 | 0.81 | ITGB3 (0.64) | ITGAVITGB3ITGB6ITGA2BITGB5 | |
| SCHEMBL24521993 | 0.78 | ITGAV (0.47) | ITGAVITGB3ITGB6ITGA2BITGB5 | |
| SCHEMBL24521946 | 0.77 | ITGAV (0.51) | ITGAVITGB3ITGB6ITGA2BITGB5 | |
| SCHEMBL29860662 | 0.76 | ITGAV (0.55) | ITGAVITGB3ITGB6ITGA2BITGB5 | |
| SCHEMBL20141940 | 0.76 | ITGAV (0.55) | ITGAVITGB3ITGB6ITGA2BITGB5 | |
| SCHEMBL20140356 | 0.76 | ITGAV (0.55) | ITGAVITGB3ITGB6ITGA2BITGB5 | |
| SCHEMBL20140354 | 0.76 | ITGAV (0.55) | ITGAVITGB3ITGB6ITGA2BITGB5 | |
| SCHEMBL20140186 | 0.75 | ITGB3 (0.49) | ITGAVITGB3ITGB6ITGA2B | |
| SCHEMBL20153415 | 0.75 | ITGAV (0.57) | ITGAVITGB3ITGB6ITGA2BITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538525-B1 | 3-SUBSTITUTED PROPIONIC ACIDS AS ALPHA V INTEGRIN INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2022-06-22 | — | — | EP | disclosed |