Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.48 |
| ▸ | ITGAV | P06756 | 20/20 | 0.48 |
| ▸ | ITGB5 | P18084 | 11/20 | 0.48 |
| ▸ | ITGB6 | P18564 | 6/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.46 |
| ▸ | ITGB8 | P26012 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24521885 | 0.81 | ITGB3 (0.45) | ITGB3ITGAVITGB5ITGB6ITGB1 | |
| SCHEMBL21294647 | 0.81 | ITGAV (0.64) | ITGB3ITGAVITGB5ITGB6ITGB1 | |
| SCHEMBL20142691 | 0.80 | ITGB3 (0.54) | ITGB3ITGAVITGB5ITGB6ITGA2B | |
| SCHEMBL21294611 | 0.80 | ITGB3 (0.54) | ITGB3ITGAVITGB5ITGB6ITGA2B | |
| SCHEMBL20142687 | 0.80 | ITGB3 (0.54) | ITGB3ITGAVITGB5ITGB6ITGA2B | |
| SCHEMBL30850840 | 0.80 | ITGB3 (0.54) | ITGB3ITGAVITGB5ITGB6ITGA2B | |
| SCHEMBL20153320 | 0.76 | ITGAV (0.66) | ITGB3ITGAVITGB5ITGB6ITGA2B | |
| SCHEMBL20153380 | 0.76 | ITGAV (0.54) | ITGB3ITGAVITGB5ITGB6ITGA2B | |
| SCHEMBL20140379 | 0.76 | ITGAV (0.56) | ITGB3ITGAVITGB5ITGB6ITGA2B | |
| SCHEMBL20140372 | 0.76 | ITGAV (0.56) | ITGB3ITGAVITGB5ITGB6ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538525-B1 | 3-SUBSTITUTED PROPIONIC ACIDS AS ALPHA V INTEGRIN INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2022-06-22 | — | — | EP | disclosed |