SCHEMBL245224

SCHEMBL245224

OCCNc1ccccn1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.61
CYP2C19 P33261 1/20 0.59
CXCR4 P61073 1/20 0.57
FABP1 P07148 1/20 0.55
FABP6 P51161 1/20 0.55
KDM4E B2RXH2 3/20 0.53
ALDH1A1 P00352 2/20 0.53
GAA P10253 2/20 0.53
POLB P06746 2/20 0.53
HPGD P15428 1/20 0.53
CYP2D6 P10635 1/20 0.51
FDPS P14324 1/20 0.50
NPC1 O15118 1/20 0.48
PKM P14618 1/20 0.48
RAB9A P51151 1/20 0.48
MAPK1 P28482 1/20 0.47
MEN1 O00255 1/20 0.47
MAPK10 P53779 1/20 0.47
GFER P55789 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5175930 0.98 CYP1A2 (0.59) CYP1A2CYP2C19CXCR4FABP1FABP6
Hydrochloric Acid SCHEMBL5175818 0.98 CYP1A2 (0.59) CYP1A2CYP2C19CXCR4FABP1FABP6
SCHEMBL30084988 0.88 CYP1A2 (0.58) CYP1A2CYP2C19CXCR4FABP1FABP6
SCHEMBL853671 0.88 CYP1A2 (0.58) CYP1A2CYP2C19CXCR4FABP1FABP6
SCHEMBL3265804 0.87 CYP1A2 (0.70) CYP1A2CYP2C19CXCR4FABP1FABP6
SCHEMBL6302675 0.86 CYP1A2 (0.56) CYP1A2CYP2C19CXCR4FABP1FABP6
SCHEMBL19874499 0.86 CYP1A2 (0.56) CYP1A2CYP2C19CXCR4FABP1FABP6
SCHEMBL6301834 0.85 CYP1A2 (0.54) CYP1A2CYP2C19CXCR4FABP1FABP6
SCHEMBL15785585 0.83
SCHEMBL10861718 0.83 CYP1A2 (0.66) CYP1A2CYP2C19CXCR4FABP1FABP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1264371-A Pyrazine derivatives, their preparation and medicines containing them RHONE POULENC RORER SA (FR) 2000-08-23 CN claimed
EP-0301348-B1 SUBSTITUTED PYRIDYL ETHANOL AMINE, PROCESS FOR THEIR PRODUCTION AND THEIR USE AS ANIMAL GROWTH PROMOTERS BAYER AG (DE) 1993-02-03 EP claimed
EP-0305845-B1 PYRIDYL ETHANOL AMINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION Dr. Karl Thomae GmbH (DE) 1992-10-28 EP claimed
US-4988694-A Promoters for animal growth regulators for animal feeds BAYER AKTIENGESELLSCHAFT (DE) 1991-01-29 US claimed
US-4920136-A Substituted pyridylethanolamine livestock production promoters BAYER AKTIENGESELLSCHAFT (DE) 1990-04-24 US claimed
EP-0305845-A1 Pyridyl ethanol amines, pharmaceutical compositions containing them and processes for their preparation Dr. Karl Thomae GmbH (DE) 1989-03-08 EP claimed
EP-0301348-A2 Substituted pyridyl ethanol amine, process for their production and their use as animal growth promoters BAYER AG (DE) 1989-02-01 EP claimed
JP-2131468-A None JP disclosed
JP-1031767-A None JP disclosed
JP-10251254-A None JP disclosed
JP-1031768-A None JP disclosed
US-20250230147-A1 LACTAMS AS CBL-B INHIBITORS GENENTECH, INC. (US) 2025-07-17 US disclosed
EP-3426246-B1 THIAZOLIDINONE COMPOUNDS AND USE THEREOF NATIONAL HEALTH RES INST (TW) 2024-05-01 EP disclosed
EP-0305845-A1 Pyridyl ethanol amines, pharmaceutical compositions containing them and processes for their preparation Dr. Karl Thomae GmbH (DE) 1989-03-08 EP disclosed
EP-0302227-A2 5-Halo-6-amino-nicotinic acid halides, their preparation and their use BAYER AG (DE) 1989-02-08 EP disclosed
EP-0301348-A2 Substituted pyridyl ethanol amine, process for their production and their use as animal growth promoters BAYER AG (DE) 1989-02-01 EP disclosed
EP-0301348-A2 Substituted pyridyl ethanol amine, process for their production and their use as animal growth promoters BAYER AG (DE) 1989-02-01 EP disclosed
EP-0299277-A2 Process for the preparation of substituted pyridyl-alkyl ketones BAYER AG (DE) 1989-01-18 EP disclosed
US-4354969-A Dye mixtures BASF AKTIENGESELLSCHAFT (DE) 1982-10-19 US disclosed
US-4033943-A Fiber reactive water soluble 2,4,6-triamino, 3-cyano pyridine-(5) azo dyestuffs CIBA-GEIGY CORPORATION (US) 1977-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250230147-A1 LACTAMS AS CBL-B INHIBITORS CBLB, CBL, CBLC CYP1A2 4351/4885CYP2C19 3530/4885CXCR4 3013/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.