Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.65 |
| ▸ | FABP1 | P07148 | 1/20 | 0.63 |
| ▸ | FABP6 | P51161 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | FDPS | P14324 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1837886 | 0.95 | CYP1A2 (0.66) | CYP1A2CYP2C19CXCR4FABP1FABP6 | |
| SCHEMBL19322388 | 0.91 | ALDH1A1 (0.67) | CYP1A2CYP2C19CXCR4FABP1FABP6 | |
| SCHEMBL10861718 | 0.91 | CYP1A2 (0.66) | CYP1A2CYP2C19CXCR4FABP1FABP6 | |
| SCHEMBL1344396 | 0.89 | CYP2C19 (0.62) | CYP1A2CYP2C19CXCR4FABP1FABP6 | |
| SCHEMBL9644591 | 0.89 | CYP1A2 (0.63) | CYP1A2CYP2C19CXCR4FABP1FABP6 | |
| SCHEMBL10858528 | 0.89 | CYP1A2 (0.63) | CYP1A2CYP2C19CXCR4FABP1FABP6 | |
| SCHEMBL1831590 | 0.88 | CYP1A2 (0.58) | CYP1A2CYP2C19CXCR4FABP1FABP6 | |
| SCHEMBL21872244 | 0.88 | CXCR4 (0.58) | CYP1A2CYP2C19CXCR4FABP1FABP6 | |
| Hydrochloric Acid SCHEMBL8177967 | 0.88 | CYP2C19 (0.61) | CYP1A2CYP2C19CXCR4FABP1FABP6 | |
| SCHEMBL8536507 | 0.87 | CYP1A2 (0.61) | CYP1A2CYP2C19CXCR4FABP1FABP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433642-B1 | Karl-Fischer reagent and process for the determination of water by using the reagent | MERCK PATENT GMBH (DE) | 1997-02-26 | — | — | EP | claimed |
| US-5086000-A | PROCESS FOR THE PREPARATION OF ALKYLENE-BIS(2-PYRIDYLAMINE) COMPOUNDS AND KARL FISCHER REAGENTS AND METHODS UTILIZING SUCH COMPOUNDS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-02-04 | — | — | US | claimed |
| JP-3170460-A | — | — | None | — | — | JP | disclosed |
| US-9074128-B2 | Metal complexes having azaborol ligands and electronic device having the same | MERCK PATENT GMBH (DE) | 2015-07-07 | — | — | US | disclosed |
| US-8722898-B2 | — | — | 2014-05-13 | — | — | US | disclosed |
| US-20120004407-A1 | METAL COMPLEXES HAVING AZABOROL LIGANDS AND ELECTRONIC DEVICE HAVING THE SAME | MERCK PATENT GMBH (DE) | 2012-01-05 | — | — | US | disclosed |
| WO-2010099852-A1 | METAL COMPLEXES HAVING AZABOROL LIGANDS AND ELECTRONIC DEVICE HAVING THE SAME | MERCK PATENT GMBH (DE) | 2010-09-10 | — | — | WO | disclosed |
| EP-0433642-B1 | Karl-Fischer reagent and process for the determination of water by using the reagent | MERCK PATENT GMBH (DE) | 1997-02-26 | — | — | EP | disclosed |
| US-5086000-A | PROCESS FOR THE PREPARATION OF ALKYLENE-BIS(2-PYRIDYLAMINE) COMPOUNDS AND KARL FISCHER REAGENTS AND METHODS UTILIZING SUCH COMPOUNDS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-02-04 | — | — | US | disclosed |
| JP-H03170460-A | PROCESS FOR PREPARATION OF ALKYLENE-BIS(2-PYRIDYLAMINE) COMPOUND | MERCK PATENT GMBH | 1991-07-24 | — | — | JP | disclosed |
| EP-0433642-A1 | Karl-Fischer reagent and process for the determination of water by using the reagent | MERCK PATENT GmbH (DE) | 1991-06-26 | — | — | EP | disclosed |
| US-4594421-A | Substituted in position 2 with a phenyl compound | RBS PHARMA (ROGER BELLON SCHOUM) S.P.A. (IT) | 1986-06-10 | — | — | US | disclosed |
| EP-0151094-A2 | Pharmacologically active imidazopyridine compounds | RBS PHARMA (ROGER BELLON SCHOUM) S.p.A. (IT) | 1985-08-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004407-A1 | METAL COMPLEXES HAVING AZABOROL LIGANDS AND ELECTRONIC DEVICE HAVING THE SAME | ICOSLG, ERAL1, CTCF | CYP1A2 1830/4885CYP2C19 2430/4885CXCR4 1277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.