Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 15/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24522446 | 0.88 | P2RX7 (0.45) | P2RX7 | |
| SCHEMBL24522493 | 0.86 | P2RX7 (0.50) | P2RX7 | |
| SCHEMBL24522398 | 0.85 | P2RX7 (0.44) | P2RX7 | |
| SCHEMBL19934952 | 0.84 | P2RX7 (0.57) | P2RX7 | |
| SCHEMBL24522494 | 0.84 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL19935086 | 0.83 | P2RX7 (0.47) | P2RX7 | |
| SCHEMBL19935149 | 0.83 | P2RX7 (0.50) | P2RX7 | |
| SCHEMBL19935231 | 0.82 | P2RX7 (0.44) | P2RX7 | |
| SCHEMBL19935108 | 0.82 | P2RX7 (0.58) | P2RX7 | |
| SCHEMBL24522491 | 0.82 | P2RX7 (0.45) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4015039-A1 | HETEROCYCLIC DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | AXXAM S.p.A. (IT) | 2022-06-22 | — | — | EP | disclosed |