Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | KDR | P35968 | 5/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19631401 | 0.82 | HDAC6 (0.72) | HDAC6TDP1KDRL3MBTL1GAA | |
| SCHEMBL29647754 | 0.82 | HDAC6 (1.00) | HDAC6TDP1KDRL3MBTL1GAA | |
| SCHEMBL19631488 | 0.82 | HDAC6 (1.00) | HDAC6TDP1KDRL3MBTL1GAA | |
| SCHEMBL15328429 | 0.81 | TDP1 (1.00) | HDAC6TDP1KDRL3MBTL1GAA | |
| SCHEMBL30061443 | 0.81 | TDP1 (1.00) | HDAC6TDP1KDRL3MBTL1GAA | |
| SCHEMBL19631338 | 0.81 | HDAC6 (0.73) | HDAC6TDP1KDRL3MBTL1GAA | |
| SCHEMBL21356262 | 0.81 | HDAC6 (0.73) | HDAC6TDP1KDRL3MBTL1GAA | |
| SCHEMBL19631371 | 0.79 | HDAC6 (0.66) | HDAC6TDP1KDRL3MBTL1GAA | |
| SCHEMBL16456332 | 0.78 | HDAC6 (0.77) | HDAC6TDP1KDRL3MBTL1GAA | |
| SCHEMBL29655132 | 0.78 | HDAC6 (0.77) | HDAC6TDP1KDRL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458444-B1 | HISTONE DEACETYLASE 6 INHIBITORS AND USE THEREOF | UNIV TAIPEI MEDICAL (TW) | 2022-06-22 | — | — | EP | disclosed |