Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3915220 | 0.84 | CYP19A1 (0.60) | CYP19A1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL24523121 | 0.84 | CYP19A1 (0.60) | CYP19A1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3922052 | 0.81 | CYP2D6 (0.61) | CYP19A1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL24522987 | 0.81 | HDAC1 (0.59) | CYP19A1KDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL3912601 | 0.81 | CYP2D6 (0.60) | CYP19A1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30803821 | 0.78 | KDM4E (0.76) | CYP19A1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11511686 | 0.78 | KDM4E (0.76) | CYP19A1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL24531791 | 0.78 | CYP19A1 (0.54) | CYP19A1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29054856 | 0.78 | HDAC1 (0.76) | CYP19A1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL24522664 | 0.78 | HDAC1 (0.55) | CYP19A1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022128832-A1 | OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |
| EP-4015512-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2022-06-22 | — | — | EP | disclosed |