Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.76 |
| ▸ | HPGD | P15428 | 5/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.76 |
| ▸ | GLA | P06280 | 1/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.76 |
| ▸ | CA12 | O43570 | 2/20 | 0.63 |
| ▸ | CA1 | P00915 | 2/20 | 0.63 |
| ▸ | CA3 | P07451 | 2/20 | 0.63 |
| ▸ | CA4 | P22748 | 2/20 | 0.63 |
| ▸ | CA5A | P35218 | 2/20 | 0.63 |
| ▸ | CA7 | P43166 | 2/20 | 0.63 |
| ▸ | CA9 | Q16790 | 2/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30803821 | 1.00 | KDM4E (0.76) | KDM4EALDH1A1HPGDHSD17B10GLA | |
| Citropten SCHEMBL29425178 | 0.86 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDHSD17B10GLA | |
| SCHEMBL15842463 | 0.86 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10GLA | |
| Citropten SCHEMBL516577 | 0.86 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDHSD17B10GLA | |
| SCHEMBL15842498 | 0.86 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10GLA | |
| SCHEMBL246219 | 0.85 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10GLA | |
| SCHEMBL14424527 | 0.84 | KDM4E (0.73) | KDM4EALDH1A1HPGDHSD17B10GLA | |
| SCHEMBL23332346 | 0.83 | ALDH1A1 (0.61) | KDM4EALDH1A1HPGDHSD17B10GLA | |
| Hymecromone Methyl Ether SCHEMBL314248 | 0.83 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10GLA | |
| Hymecromone Methyl Ether SCHEMBL31103478 | 0.83 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117599043-A | Application of dihydro-isocoumarin and derivatives thereof in preparation of medicines for treating orthopedic diseases | 中国人民解放军联勤保障部队第九二〇医院 | 2024-02-27 | — | — | CN | claimed |
| US-9127092-B2 | Method for producing polydienes and polydiene copolymers with reduced cold flow | BRIDGESTONE CORPORATION (JP) | 2015-09-08 | — | — | US | claimed |
| US-20140187725-A1 | METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW | BRIDGESTONE CORPORATION (JP) | 2014-07-03 | — | — | US | claimed |
| CN-117599043-B | Application of dihydro-isocoumarin and derivatives thereof in preparation of medicines for treating orthopedic diseases | 中国人民解放军联勤保障部队第九二〇医院 | 2024-07-09 | — | — | CN | disclosed |
| CN-117599043-B | Application of dihydro-isocoumarin and derivatives thereof in preparation of medicines for treating orthopedic diseases | 中国人民解放军联勤保障部队第九二〇医院 | 2024-07-09 | — | — | CN | disclosed |
| CN-117599043-A | Application of dihydro-isocoumarin and derivatives thereof in preparation of medicines for treating orthopedic diseases | 中国人民解放军联勤保障部队第九二〇医院 | 2024-02-27 | — | — | CN | disclosed |
| CN-117599043-A | Application of dihydro-isocoumarin and derivatives thereof in preparation of medicines for treating orthopedic diseases | 中国人民解放军联勤保障部队第九二〇医院 | 2024-02-27 | — | — | CN | disclosed |
| US-9127092-B2 | Method for producing polydienes and polydiene copolymers with reduced cold flow | BRIDGESTONE CORPORATION (JP) | 2015-09-08 | — | — | US | disclosed |
| US-20140187725-A1 | METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW | BRIDGESTONE CORPORATION (JP) | 2014-07-03 | — | — | US | disclosed |
| US-4179447-A | ANTIALLERGENS | WARNER-LAMBERT COMPANY (US) | 1979-12-18 | — | — | US | disclosed |
| US-4158663-A | FROM 4-METHOXYCOUMARINS USING SODIUM HYDRIDE AND DIMETHYLSULFOXIDE | WARNER-LAMBERT COMPANY (US) | 1979-06-19 | — | — | US | disclosed |