Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.50 |
| ▸ | FPR3 | P25089 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | AHCY | P23526 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2455745 | 0.90 | OPRD1 (0.48) | OPRD1FPR3FPR2SMN1; SMN2KDM1A | |
| SCHEMBL337262 | 0.85 | SMN1; SMN2 (0.45) | OPRD1FPR3FPR2SMN1; SMN2KDM1A | |
| SCHEMBL9354741 | 0.85 | SMN1; SMN2 (0.45) | OPRD1FPR3FPR2SMN1; SMN2KDM1A | |
| SCHEMBL2452730 | 0.82 | OPRD1 (0.47) | OPRD1FPR3FPR2SMN1; SMN2KDM1A | |
| SCHEMBL1483725 | 0.81 | OPRD1 (0.51) | OPRD1FPR3FPR2SMN1; SMN2KDM1A | |
| SCHEMBL23607634 | 0.80 | OPRD1 (0.48) | OPRD1FPR3FPR2SMN1; SMN2KDM1A | |
| SCHEMBL1779025 | 0.79 | SMN1; SMN2 (0.45) | OPRD1FPR3FPR2SMN1; SMN2KDM1A | |
| SCHEMBL863388 | 0.79 | SMN1; SMN2 (0.45) | OPRD1FPR3FPR2SMN1; SMN2KDM1A | |
| SCHEMBL20410 | 0.79 | SMN1; SMN2 (0.45) | OPRD1FPR3FPR2SMN1; SMN2KDM1A | |
| SCHEMBL13853607 | 0.79 | OPRD1 (0.54) | OPRD1FPR3FPR2SMN1; SMN2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2366700-A1 | Pyrrolidine-thioxopyrimidinone/thiohydantoin organocatolysts | National and Kapodistrian Universty of Athens (GR) | 2011-09-21 | — | — | EP | disclosed |
| EP-2366700-A1 | Pyrrolidine-thioxopyrimidinone/thiohydantoin organocatolysts | National and Kapodistrian Universty of Athens (GR) | 2011-09-21 | — | — | EP | disclosed |