Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 10/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 2/20 | 0.34 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24523713 | 0.89 | KDM4E (0.39) | TDP2KDM4EATML3MBTL1G6PD | |
| SCHEMBL24524222 | 0.87 | KDM4E (0.42) | TDP2KDM4EATML3MBTL1G6PD | |
| SCHEMBL24523790 | 0.84 | KDM4E (0.43) | TDP2KDM4EATML3MBTL1G6PD | |
| SCHEMBL24524204 | 0.84 | ATM (0.43) | TDP2KDM4EATML3MBTL1G6PD | |
| SCHEMBL24523778 | 0.83 | KDM4E (0.42) | TDP2KDM4EATML3MBTL1G6PD | |
| SCHEMBL24523716 | 0.82 | ENPP3 (0.35) | KDM4EENPP3DUSP3CYP19A1 | |
| SCHEMBL18348494 | 0.82 | KDM4E (0.42) | TDP2KDM4EATML3MBTL1DUSP3 | |
| SCHEMBL21202451 | 0.82 | KDM4E (0.41) | TDP2KDM4EATML3MBTL1G6PD | |
| SCHEMBL18348362 | 0.82 | KDM4E (0.41) | TDP2KDM4EATML3MBTL1G6PD | |
| SCHEMBL24523765 | 0.81 | PTGDR2 (0.40) | G6PDENPP3CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129116-A1 | INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |