Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.77 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.77 |
| ▸ | MEN1 | O00255 | 4/20 | 0.71 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2450380 | 0.95 | ALDH1A1 (0.90) | ALDH1A1KMT2APTK2BMEN1PKM | |
| SCHEMBL2451111 | 0.95 | ALDH1A1 (0.90) | ALDH1A1KMT2APTK2BMEN1PKM | |
| SCHEMBL2049483 | 0.92 | ALDH1A1 (0.89) | ALDH1A1KMT2APTK2BMEN1KDM4E | |
| SCHEMBL30211332 | 0.92 | ALDH1A1 (0.89) | ALDH1A1KMT2APTK2BMEN1KDM4E | |
| SCHEMBL2452529 | 0.90 | ALDH1A1 (0.81) | ALDH1A1KMT2APTK2BMEN1PKM | |
| SCHEMBL2451600 | 0.89 | ALDH1A1 (0.79) | ALDH1A1KMT2APTK2BMEN1PKM | |
| SCHEMBL2451339 | 0.89 | ALDH1A1 (0.79) | ALDH1A1KMT2APTK2BMEN1PKM | |
| SCHEMBL14383944 | 0.87 | ALDH1A1 (0.77) | ALDH1A1KMT2APTK2BMEN1KDM4E | |
| SCHEMBL24801375 | 0.87 | ALDH1A1 (1.00) | ALDH1A1KMT2APTK2BMEN1KDM4E | |
| SCHEMBL14964190 | 0.87 | ALDH1A1 (1.00) | ALDH1A1KMT2APTK2BMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022072-B2 | Azolylmethylidenehydrazine derivative and use thereof | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2011-09-20 | — | — | US | disclosed |
| US-20100190754-A1 | AZOLYLMETHYLIDENEHYDRAZINE DERIVATIVE AND USE THEREOF | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2010-07-29 | — | — | US | disclosed |
| EP-2168951-A1 | AZOLYLMETHYLENEHYDRAZINE DERIVATIVE AND USE THEREOF | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2010-03-31 | — | — | EP | disclosed |
| US-5925780-A | VIRICIDES FOR RETROVIRAL SPECIES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1999-07-20 | — | — | US | disclosed |
| US-5728718-A | RETROVIRAL PROTEASE INHIBITOR; TREATMENT OF HTLV | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-03-17 | — | — | US | disclosed |
| US-4728633-A | HEAT AND PRESSURE SENSITIVE ELEMENTS | FUJI PHOTO FILM CO., LTD. (JP) | 1988-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190754-A1 | AZOLYLMETHYLIDENEHYDRAZINE DERIVATIVE AND USE THEREOF | ARSA, AHR, HRH2 | ALDH1A1 831/4885KMT2A 1190/4885PTK2B 1476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.