Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 3/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 2/20 | 0.46 |
| ▸ | MC5R | P33032 | 2/20 | 0.46 |
| ▸ | MC3R | P41968 | 2/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL466696 | 1.00 | HTR2A (0.55) | HTR2AHTR2CHTR2BDPP4TACR1 | |
| SCHEMBL237566 | 0.87 | HTR2A (0.57) | HTR2AHTR2CHTR2BDPP4TACR1 | |
| SCHEMBL4633497 | 0.87 | HTR2A (0.57) | HTR2AHTR2CHTR2BDPP4TACR1 | |
| SCHEMBL5845125 | 0.87 | HTR2A (0.57) | HTR2AHTR2CHTR2BDPP4TACR1 | |
| Hydrochloric Acid SCHEMBL2896538 | 0.85 | HTR2A (0.55) | HTR2AHTR2CHTR2BDPP4TACR1 | |
| Hydrochloric Acid SCHEMBL4633494 | 0.85 | HTR2A (0.55) | HTR2AHTR2CHTR2BDPP4TACR1 | |
| SCHEMBL839749 | 0.85 | HTR2A (0.55) | HTR2AHTR2CHTR2BDPP4TACR1 | |
| Hydrochloric Acid SCHEMBL237565 | 0.85 | HTR2A (0.55) | HTR2AHTR2CHTR2BDPP4TACR1 | |
| SCHEMBL839943 | 0.85 | HTR2A (0.55) | HTR2AHTR2CHTR2BDPP4TACR1 | |
| SCHEMBL22995865 | 0.84 | HTR2A (0.58) | HTR2AHTR2CHTR2BDPP4TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1909814-B1 | Peptides for induction and enhancement of apoptosis in tumor cells | GEORG AUGUST UNIVERSITÄT GÖTTINGEN STIFTUNG ÖFFENTLICHEN RECHTS OHNE BEREICH HUMANMEDIZIN (DE) | 2015-06-24 | — | — | EP | disclosed |
| US-8334258-B2 | Administering gonadotropin-hormone-releasing hormone (GnRH) antagonist peptide for inducing/enhancing apoptosis of breast cancer or malignant melanoma or gynaecological cancer | GEORG-AUGUST-UNIVERSITÄT GÖTTINGEN STIFTUNG ÖFFENTLICHEN RECHTS (UNIVERSITÄTSMEDIZIN) (DE) | 2012-12-18 | — | — | US | disclosed |
| US-20120004182-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR INDUCTION AND ENHANCEMENT OF APOPTOSIS IN TUMOR CELLS | GEORG-AUGUST-UNIVERSITAET GOETTINGEN STIFTUNG OEFFENTLICHEN RECHTS, UNIVERSITAETSMEDIZIN (DE) | 2012-01-05 | — | — | US | disclosed |
| US-20080167250-A1 | Method For Induction and Enhancement of Apoptosis In Tumor Cells | GEORG-AUGUST-UNIVERSITAET GOETTINGEN, STIFTUNG OEFFENTLECHEN RECHTS, BEREICH HUMANMEDIZIN (DE) | 2008-07-10 | — | — | US | disclosed |
| EP-1909814-A1 | METHOD FOR INDUCTION AND ENHANCEMENT OF APOPTOSIS IN TUMOR CELLS | Georg-August-Universität Göttingen Stiftung des Öffentlichen Rechts (Bereich Humanmedizin) (DE) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007012430-A1 | METHOD FOR INDUCTION AND ENHANCEMENT OF APOPTOSIS IN TUMOR CELLS | GEORG-AUGUST-UNIVERSITÄT-GÖTTINGEN (DE) | 2007-02-01 | — | — | WO | disclosed |