Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 3/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 2/20 | 0.46 |
| ▸ | MC5R | P33032 | 2/20 | 0.46 |
| ▸ | MC3R | P41968 | 2/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL245249 | 1.00 | HTR2A (0.55) | HTR2AHTR2CHTR2BDPP4TACR1 | |
| SCHEMBL237566 | 0.87 | HTR2A (0.57) | HTR2AHTR2CHTR2BDPP4TACR1 | |
| SCHEMBL4633497 | 0.87 | HTR2A (0.57) | HTR2AHTR2CHTR2BDPP4TACR1 | |
| SCHEMBL5845125 | 0.87 | HTR2A (0.57) | HTR2AHTR2CHTR2BDPP4TACR1 | |
| Hydrochloric Acid SCHEMBL2896538 | 0.85 | HTR2A (0.55) | HTR2AHTR2CHTR2BDPP4TACR1 | |
| Hydrochloric Acid SCHEMBL4633494 | 0.85 | HTR2A (0.55) | HTR2AHTR2CHTR2BDPP4TACR1 | |
| SCHEMBL839749 | 0.85 | HTR2A (0.55) | HTR2AHTR2CHTR2BDPP4TACR1 | |
| Hydrochloric Acid SCHEMBL237565 | 0.85 | HTR2A (0.55) | HTR2AHTR2CHTR2BDPP4TACR1 | |
| SCHEMBL839943 | 0.85 | HTR2A (0.55) | HTR2AHTR2CHTR2BDPP4TACR1 | |
| SCHEMBL22995865 | 0.84 | HTR2A (0.58) | HTR2AHTR2CHTR2BDPP4TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2585486-B1 | NEW OCTAPEPTIDIC COMPOUNDS AND THEIR USE IN THERAPY | IPSEN PHARMA SAS (FR) | 2014-05-14 | — | — | EP | disclosed |
| US-20130252892-A1 | NOVEL OCTAPEPTIDE COMPOUNDS AND THERAPEUTIC USE THEREOF | IPSEN PHARMA S.A.S (FR) | 2013-09-26 | — | — | US | disclosed |
| EP-2399931-A1 | New octapeptide compounds and their therapeutic use | IPSEN PHARMA S.A.S. (FR) | 2011-12-28 | — | — | EP | disclosed |
| US-6153587-A | Conformationally constrained LH-RH analogues, their uses and pharmaceutical compositions containing them | LABORATOIRE THERAMEX (MC) | 2000-11-28 | — | — | US | disclosed |
| EP-0937101-B1 | CONFORMATIONALLY CONSTRAINED LH-RH ANALOGUES, THEIR USES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | THERAMEX (MC) | 2000-10-11 | — | — | EP | disclosed |
| EP-0937101-A1 | CONFORMATIONALLY CONSTRAINED LH-RH ANALOGUES, THEIR USES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LABORATOIRE THERAMEX (MC) | 1999-08-25 | — | — | EP | disclosed |
| WO-1998021229-A1 | CONFORMATIONALLY CONSTRAINED LH-RH ANALOGUES, THEIR USES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LABORATOIRE THERAMEX (MC) | 1998-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130252892-A1 | NOVEL OCTAPEPTIDE COMPOUNDS AND THERAPEUTIC USE THEREOF | SSTR5, SSTR4, SSTR3 | HTR2A 441/4885HTR2C 540/4885HTR2B 504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.