Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 16/20 | 0.43 |
| ▸ | JAK2 | O60674 | 10/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26810184 | 0.88 | PDE4B (0.38) | JAK1JAK2 | |
| SCHEMBL24526028 | 0.88 | JAK1 (0.42) | JAK1JAK2 | |
| SCHEMBL24525906 | 0.86 | JAK1 (0.44) | JAK1JAK2 | |
| SCHEMBL24526227 | 0.86 | JAK1 (0.43) | JAK1JAK2 | |
| SCHEMBL26810148 | 0.84 | JAK1 (0.46) | JAK1JAK2 | |
| SCHEMBL24525943 | 0.84 | JAK1 (0.44) | JAK1JAK2 | |
| SCHEMBL24525904 | 0.84 | JAK1 (0.45) | JAK1JAK2 | |
| SCHEMBL24526138 | 0.83 | JAK1 (0.45) | JAK1JAK2CHRM4 | |
| SCHEMBL24526213 | 0.83 | LMNA (0.41) | JAK1JAK2 | |
| SCHEMBL24526230 | 0.83 | JAK1 (0.44) | JAK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827657-B2 | Boron containing pyrazole compounds, compositions comprising them, methods and uses thereof | Boehringer Ingelheim Animal Health USA Inc. (US) | 2023-11-28 | — | — | US | disclosed |
| US-11827657-B2 | Boron containing pyrazole compounds, compositions comprising them, methods and uses thereof | Boehringer Ingelheim Animal Health USA Inc. (US) | 2023-11-28 | — | — | US | disclosed |
| US-20220194965-A1 | BORON CONTAINING PYRAZOLE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF | BORAH, INC. | 2022-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11827657-B2 | Boron containing pyrazole compounds, compositions comprising them, methods and uses thereof | JAK3, JAK1, JAK2 | JAK1 2/4885JAK2 3/4885CHRM4 4768/4885 |
| US-20220194965-A1 | BORON CONTAINING PYRAZOLE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF | JAK3, JAK1, JAK2 | JAK1 2/4885JAK2 3/4885CHRM4 4768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.