Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18878233 | 0.82 | PARP1 (0.48) | PARP1 | |
| SCHEMBL10311104 | 0.80 | PRMT5 (0.45) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL839470 | 0.80 | PRMT5 (0.45) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13741356 | 0.79 | ALDH1A1 (0.48) | HSD17B10MEN1KMT2AKDM4ECA12 | |
| Hydrochloric Acid SCHEMBL10277298 | 0.78 | PRMT5 (0.45) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29486090 | 0.78 | HSD17B10 (0.44) | HSD17B10MEN1KMT2ALMNAKDM4E | |
| SCHEMBL24851934 | 0.78 | HSD17B10 (0.44) | HSD17B10MEN1KMT2ALMNAKDM4E | |
| SCHEMBL3622823 | 0.78 | TLR9 (0.43) | KCNH2HSD17B10MEN1KMT2ALMNA | |
| SCHEMBL18863625 | 0.77 | MEN1 (0.36) | PARP1HSD17B10MEN1KMT2ALMNA | |
| SCHEMBL13406258 | 0.77 | ALDH1A1 (0.43) | HSD17B10MEN1KMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129047-A2 | NOVEL MODULATORS OF THE NMDA RECEPTOR | H. LUNDBECK A/S (DK) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022129047-A2 | NOVEL MODULATORS OF THE NMDA RECEPTOR | H. LUNDBECK A/S (DK) | 2022-06-23 | — | — | WO | disclosed |