Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 20/20 | 0.87 |
| ▸ | TRPV4 | Q9HBA0 | 9/20 | 0.87 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.73 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2444060 | 0.93 | TRPA1 (1.00) | TRPA1TRPV4TRPV1TRPV3 | |
| SCHEMBL10275261 | 0.92 | TRPA1 (1.00) | TRPA1TRPV4TRPV1TRPV3 | |
| SCHEMBL2445731 | 0.88 | TRPA1 (1.00) | TRPA1TRPV4TRPV1TRPV3 | |
| SCHEMBL2445784 | 0.85 | TRPA1 (1.00) | TRPA1TRPV4TRPV3 | |
| SCHEMBL10275206 | 0.85 | TRPA1 (1.00) | TRPA1TRPV4TRPV1TRPV3 | |
| SCHEMBL9932587 | 0.85 | TRPA1 (1.00) | TRPA1TRPV4TRPV1TRPV3 | |
| SCHEMBL14376705 | 0.84 | TRPA1 (0.86) | TRPA1TRPV4TRPV1TRPV3 | |
| SCHEMBL474671 | 0.82 | TRPA1 (0.77) | TRPA1TRPV4TRPV1TRPV3 | |
| SCHEMBL14972753 | 0.82 | TRPA1 (0.77) | TRPA1TRPV4TRPV1TRPV3 | |
| SCHEMBL612877 | 0.81 | TRPA1 (0.72) | TRPA1TRPV4TRPV1TRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011114184-A1 | AMIDES OF HETEROCYCLIC COMPOUNDS AS TRPA1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2011-09-22 | — | — | WO | claimed |