Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 4/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.32 |
| ▸ | ACVR2A | P27037 | 2/20 | 0.31 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24387010 | 0.89 | HCRTR2 (0.34) | HCRTR2 | |
| SCHEMBL24387056 | 0.89 | HCRTR2 (0.34) | HCRTR2TLR8TLR7TLR9 | |
| Hydrochloric Acid SCHEMBL29750119 | 0.88 | HCRTR2 (0.33) | HCRTR2TLR8TLR7TLR9 | |
| SCHEMBL27181053 | 0.87 | HCRTR2 (0.43) | HCRTR2 | |
| SCHEMBL27181057 | 0.87 | HCRTR2 (0.43) | HCRTR2 | |
| SCHEMBL24529568 | 0.82 | HCRTR2 (0.57) | HCRTR2 | |
| SCHEMBL24529391 | 0.82 | HCRTR2 (0.44) | HCRTR2 | |
| SCHEMBL24387527 | 0.81 | HCRTR2 (0.39) | HCRTR2TLR8TLR7TLR9 | |
| SCHEMBL24529427 | 0.80 | HCRTR2 (0.33) | HCRTR2TLR8TLR7TLR9ACVR2A | |
| SCHEMBL24529233 | 0.79 | HCRTR2 (0.41) | HCRTR2TLR8TLR7TLR9PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022132696-A1 | UREA OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2022-06-23 | — | — | WO | disclosed |