Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.49 |
| ▸ | CTSB | P07858 | 4/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29144580 | 0.85 | CTSL (0.56) | CTSLCTSBCAPN1 | |
| SCHEMBL24530134 | 0.84 | CTSL (0.53) | CTSLCTSBCAPN1 | |
| SCHEMBL24530133 | 0.82 | CTSL (0.60) | CTSLCTSB | |
| SCHEMBL24530132 | 0.81 | CTSL (0.57) | CTSLCTSBCAPN1CTSSCTSK | |
| SCHEMBL29144557 | 0.81 | CTSL (0.53) | CTSLCTSB | |
| SCHEMBL24530137 | 0.81 | CTSL (0.53) | CTSLCTSB | |
| SCHEMBL23836138 | 0.77 | — | — | |
| SCHEMBL34468082 | 0.77 | — | — | |
| SCHEMBL23836173 | 0.77 | — | — | |
| SCHEMBL29063274 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129953-A1 | SARS-COV-2 MPRO INHIBITOR COMPOUNDS | HEPTARES THERAPEUTICS LIMITED (GB) | 2022-06-23 | — | — | WO | disclosed |