SCHEMBL245302

SCHEMBL245302

CC(C)C1COC(c2cccc(C3=NC(C(C)C)CO3)n2)=N1

nearest known ligand 0.66

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.66
MAPT P10636 1/20 0.61
RAB9A P51151 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31069783 1.00 NPC1 (0.66) NPC1MAPTRAB9ASMN1; SMN2MEN1
SCHEMBL21351775 1.00 NPC1 (0.66) NPC1MAPTRAB9ASMN1; SMN2MEN1
SCHEMBL30106823 1.00 NPC1 (0.66) NPC1MAPTRAB9ASMN1; SMN2MEN1
SCHEMBL14148163 1.00 NPC1 (0.66) NPC1MAPTRAB9ASMN1; SMN2MEN1
SCHEMBL918871 1.00 NPC1 (0.66) NPC1MAPTRAB9ASMN1; SMN2MEN1
SCHEMBL245303 1.00 NPC1 (0.66) NPC1MAPTRAB9ASMN1; SMN2MEN1
SCHEMBL12786269 0.98 NPC1 (0.64) NPC1MAPTRAB9ASMN1; SMN2MEN1
Hydrochloric Acid SCHEMBL7183038 0.97 NPC1 (0.62) NPC1MAPTRAB9ASMN1; SMN2MEN1
Hydrochloric Acid SCHEMBL7171153 0.97 NPC1 (0.62) NPC1MAPTRAB9ASMN1; SMN2MEN1
Hydrochloric Acid SCHEMBL7182624 0.97 NPC1 (0.62) NPC1MAPTRAB9ASMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026047173-A1 PROCESS FOR PREPARING SUSTAINABLE JET FUELS OR DIESEL FUELS; AND PRECURSORS THEREOF Terra Mater BV (BE) 2026-03-05 WO claimed
EP-4622945-A1 OLIGOMERISATION OF ALCOHOLS Terra Mater BV (BE) 2025-10-01 EP claimed
CN-120040461-A Spirobarbitudes compound, preparation method and application 北京工业大学 2025-05-27 CN claimed
CN-120040462-A Spiropyrazinone compound, preparation method and application 北京工业大学 2025-05-27 CN claimed
US-20250092008-A1 PROCESS FOR MAKING AN EP4 ANTAGONIST ONO PHARMACEUTICAL CO., LTD. (JP) 2025-03-20 US claimed
EP-4384509-A1 PROCESS FOR MAKING AN EP4 ANTAGONIST ONO Pharmaceutical Co., Ltd. (JP) 2024-06-19 EP claimed
WO-2024110575-A1 OLIGOMERISATION OF ALCOHOLS Terra Mater BV (BE) 2024-05-30 WO claimed
CN-116813643-A Chiral oxo-bridged oxazolyl heterocyclic compound and preparation method thereof 北京工业大学 2023-09-29 CN claimed
WO-2023017813-A1 PROCESS FOR MAKING AN EP4 ANTAGONIST ONO PHARMACEUTICAL CO., LTD. (JP) 2023-02-16 WO claimed
US-8735586-B2 Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles SANOFI (FR) 2014-05-27 US claimed
US-20100216988-A1 Regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles SANOFI-AVENTIS (FR) 2010-08-26 US claimed
EP-2173747-A1 A REGIOSELECTIVE METAL CATALYZED SYNTHESIS OF ANNELATED BENZIMIDAZOLES AND AZABENZIMIDAZOLES Sanofi-Aventis (FR) 2010-04-14 EP claimed
EP-2173721-A1 A REGIOSELECTIVE COPPER CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES Sanofi-Aventis (FR) 2010-04-14 EP claimed
US-7524594-B2 Photosensitive dielectric resin compositions, films formed therefrom and semiconductor and display devices encompassing such films PROMERUS LLC (US) 2009-04-28 US claimed
WO-2009000413-A1 A REGIOSELECTIVE COPPER CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES SANOFI-AVENTIS (FR) 2008-12-31 WO claimed
WO-2009000412-A1 A REGIOSELECTIVE METAL CATALYZED SYNTHESIS OF ANNELATED BENZIMIDAZOLES AND AZABENZIMIDAZOLES SANOFI AVENTIS (FR) 2008-12-31 WO claimed
EP-1778759-B1 PHOTOSENSITIVE DIELECTRIC RESIN COMPOSITIONS AND THEIR USES PROMERUS LLC (US) 2008-11-12 EP claimed
EP-1778759-A1 PHOTOSENSITIVE DIELECTRIC RESIN COMPOSITIONS AND THEIR USES Promerus, LLC (US) 2007-05-02 EP claimed
WO-2006017035-A1 PHOTOSENSITIVE DIELECTRIC RESIN COMPOSITIONS AND THEIR USES PROMERUS LLC (US) 2006-02-16 WO claimed
US-20060008734-A1 Photosensitive dielectric resin compositions, films formed therefrom and semiconductor and display devices encompassing such films SUMITOMO BAKELITE CO., LTD. (JP) 2006-01-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250092008-A1 PROCESS FOR MAKING AN EP4 ANTAGONIST PTGER4, LTB4R2, EPB41 NPC1 3834/4885MAPT 4859/4885RAB9A 4333/4885
US-20100216988-A1 Regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles AZI2, NIT2, NISCH NPC1 3174/4885MAPT 4209/4885RAB9A 2309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.