Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL245302 | 1.00 | NPC1 (0.66) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL31069783 | 1.00 | NPC1 (0.66) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL21351775 | 1.00 | NPC1 (0.66) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL30106823 | 1.00 | NPC1 (0.66) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL14148163 | 1.00 | NPC1 (0.66) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL918871 | 1.00 | NPC1 (0.66) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL12786269 | 0.98 | NPC1 (0.64) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL7183038 | 0.97 | NPC1 (0.62) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL7171153 | 0.97 | NPC1 (0.62) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL7182624 | 0.97 | NPC1 (0.62) | NPC1MAPTRAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 348 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260110689-A1 | METHODS AND COMPOSITIONS RELATED TO MODIFIED FLUOROPHORES | UNIV TEXAS (US) | 2026-04-23 | — | — | US | claimed |
| CN-120040462-A | Spiropyrazinone compound, preparation method and application | 北京工业大学 | 2025-05-27 | — | — | CN | claimed |
| CN-120040440-A | Chiral pyridine bisoxazoline ligand modified by pyridine ring C4-position alkyl derivative, and synthetic method and application thereof | 华东师范大学 | 2025-05-27 | — | — | CN | claimed |
| CN-119977740-A | Catalytic synthesis method of chiral polysubstituted hydrogenated quinoline compound | 中国海洋大学 | 2025-05-13 | — | — | CN | claimed |
| US-20250092008-A1 | PROCESS FOR MAKING AN EP4 ANTAGONIST | ONO PHARMACEUTICAL CO., LTD. (JP) | 2025-03-20 | — | — | US | claimed |
| CN-118724927-A | Chiral heteroleptic nine-coordination rare earth complex and preparation method and application thereof | 西京学院 | 2024-10-01 | — | — | CN | claimed |
| CN-118580231-A | PyBox ligand modified by pyridine ring C4 hydrogen bond donor receptor, and synthetic method and application thereof | 华东师范大学 | 2024-09-03 | — | — | CN | claimed |
| EP-4384509-A1 | PROCESS FOR MAKING AN EP4 ANTAGONIST | ONO Pharmaceutical Co., Ltd. (JP) | 2024-06-19 | — | — | EP | claimed |
| CN-113666862-B | Method for preparing chiral 3-nitroindole compounds through nickel-catalyzed asymmetric nitration reaction | 山东大学 | 2024-05-31 | — | — | CN | claimed |
| CN-115739188-B | Cyclized heterogeneous catalyst, preparation method thereof and application thereof in preparation of L-isopulegol from R-citronellal | 山东新和成药业有限公司 | 2024-02-13 | — | — | CN | claimed |
| WO-2009000412-A1 | A REGIOSELECTIVE METAL CATALYZED SYNTHESIS OF ANNELATED BENZIMIDAZOLES AND AZABENZIMIDAZOLES | SANOFI AVENTIS (FR) | 2008-12-31 | — | — | WO | claimed |
| EP-0887400-B9 | Fuel composition containing an aliphatic amine and a poly (oxyalkylene) monool | CHEVRON ORONITE CO (US) | 2005-01-19 | — | — | EP | claimed |
| EP-0887400-B1 | Fuel composition containing an aliphatic amine and a poly (oxyalkylene) monool | CHEVRON ORONITE CO (US) | 2004-09-29 | — | — | EP | claimed |
| US-6511518-B1 | Antideposit agents for internal combustion engines comprising polyethers, addition polymers, carboxylic acids and reaction products of polyalkylphenols, amines and aldehydes | CHEVRON ORONITE COMPANY LLC | 2003-01-28 | — | — | US | claimed |
| US-6271400-B2 | SILICON BASED ANHYDROUS OXIDANT; LIGAND; CATALYTIC ORGANO OR INORGANO RHENIUM OXIDE; CONTROLLING EXCESS WATER CONCENTRATION AND MAXIMIZING MONOPEROXOCOMPLEX FORMATION. | THE SCRIPPS RESEARCH INSTITUTE | 2001-08-07 | — | — | US | claimed |
| US-20010001798-A1 | EPOXIDATION OF OLEFINS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2001-05-24 | — | — | US | claimed |
| US-5993499-A | HYDROCARBYL (MOL. WT.700-3,000)-SUBSTITUTED AMINE HAVING AT LEAST ONE BASIC NITROGEN ATOM AND A HYDROCARBYL-TERMINATED POLY(OXYALKYLENE) MONOOL HAVING AN AVERAGE MOLECULAR WEIGHT OF 500-5,000. | CHEVRON CHEMICAL COMPANY (US) | 1999-11-30 | — | — | US | claimed |
| EP-0887400-A1 | Fuel composition containing an aliphatic amine and a poly (oxyalkylene) monool | Chevron Chemical Company LLC (US) | 1998-12-30 | — | — | EP | claimed |
| WO-1998033786-A9 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | — | 1998-12-30 | — | — | WO | claimed |
| WO-1998033786-A1 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-08-06 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250092008-A1 | PROCESS FOR MAKING AN EP4 ANTAGONIST | PTGER4, LTB4R2, EPB41 | NPC1 3834/4885MAPT 4859/4885RAB9A 4333/4885 |
| US-20260110689-A1 | METHODS AND COMPOSITIONS RELATED TO MODIFIED FLUOROPHORES | NONO, SIGMAR1, HTR3D | NPC1 2181/4885MAPT 1590/4885RAB9A 4612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.