Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 16/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13678434 | 1.00 | CRBN (0.40) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL675922 | 0.80 | CRBN (0.43) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL376892 | 0.77 | — | — | |
| SCHEMBL677173 | 0.74 | CRBN (0.49) | CRBNDDB1ALDH1A1 | |
| SCHEMBL20206912 | 0.71 | CRBN (0.46) | CRBNDDB1 | |
| SCHEMBL22558593 | 0.70 | CRBN (0.45) | CRBNDDB1IKZF3 | |
| SCHEMBL23065982 | 0.69 | CRBN (0.35) | CRBNDDB1 | |
| SCHEMBL895166 | 0.69 | — | — | |
| SCHEMBL20359431 | 0.69 | CRBN (0.44) | CRBNDDB1 | |
| SCHEMBL14878 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107315263-B | The preparation method of Silica hydrogel contact lens surface method of modifying and its colorful contact lens | 江苏彩康隐形眼镜有限公司 | 2019-03-29 | — | — | CN | claimed |
| CN-107315263-A | The preparation method of Silica hydrogel contact lens surface method of modifying and its colorful contact lens | 江苏彩康隐形眼镜有限公司 | 2017-11-03 | — | — | CN | claimed |
| WO-2022132603-A1 | PDE4 DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2022-06-23 | — | — | WO | disclosed |
| CN-105916895-B | Improve the water-based paint compositions of open hour | 欧尼克斯荷兰有限公司 | 2019-04-19 | — | — | CN | disclosed |
| CN-107315263-B | The preparation method of Silica hydrogel contact lens surface method of modifying and its colorful contact lens | 江苏彩康隐形眼镜有限公司 | 2019-03-29 | — | — | CN | disclosed |
| CN-107921296-A | Tooth whitening oral care composition | 高露洁-棕榄公司 | 2018-04-17 | — | — | CN | disclosed |