Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20206912 | 0.81 | CRBN (0.46) | CRBNDDB1HTT | |
| Succinimide SCHEMBL7975792 | 0.81 | CRBN (0.39) | CRBNDDB1ALDH1A1 | |
| SCHEMBL288567 | 0.80 | ALDH1A1 (0.44) | CRBNDDB1ALDH1A1 | |
| SCHEMBL20359431 | 0.79 | CRBN (0.44) | CRBNDDB1HTT | |
| SCHEMBL29044524 | 0.78 | ALDH1A1 (0.42) | CRBNDDB1ALDH1A1 | |
| SCHEMBL8952307 | 0.78 | CRBN (0.43) | CRBNDDB1 | |
| SCHEMBL9028497 | 0.76 | CRBN (0.42) | CRBNDDB1 | |
| Boric Acid SCHEMBL4457542 | 0.74 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL24113857 | 0.74 | CRBN (0.57) | CRBNDDB1HTT | |
| SCHEMBL21635270 | 0.74 | CRBN (0.53) | CRBNDDB1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102449748-A | Photolithographically defined contacts to carbon nanostructures | UNIV PENNSYLVANIA | 2012-05-09 | — | — | CN | claimed |
| EP-0409481-A2 | Graft copolymers and a process for their preparation | ROHM AND HAAS COMPANY (US) | 1991-01-23 | — | — | EP | claimed |
| JP-3115434-A | — | — | None | — | — | JP | disclosed |
| US-11174271-B2 | 6-membered uracil isosteres | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2021-11-16 | — | — | US | disclosed |
| US-10544105-B2 | Deoxyuridine triphosphatase inhibitors containing cyclopropano linkage | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2020-01-28 | — | — | US | disclosed |
| US-20190270756-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2019-09-05 | — | — | US | disclosed |
| US-20180201586-A1 | DEOXYURIDINE TRIPHOSPHATASE INHIBITORS CONTAINING CYCLOPROPANO LINKAGE | SAI LIFE SCIENCES LIMITED (IN) | 2018-07-19 | — | — | US | disclosed |
| WO-2018098204-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |
| US-8957056-B2 | Migrastatin analogs in the treatment of cancer | SLOAN-KETTERING INSTIUTE FOR CANCER RESEARCH (US) | 2015-02-17 | — | — | US | disclosed |
| US-8835693-B2 | Migrastatin analogs and uses thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2014-09-16 | — | — | US | disclosed |
| US-20140011844-A1 | MIGRASTATIN ANALOGS AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2014-01-09 | — | — | US | disclosed |
| CN-1036564-C | Herbicidal glutarmides | ROHM & HAAS (US) | 1997-12-03 | — | — | CN | disclosed |
| EP-0658160-A1 | ANTIPSYCHOTIC QUINOLINE DERIVATIVES OF BENZODIOXANMETHYLAMINE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-06-21 | — | — | EP | disclosed |
| EP-0409481-B1 | Graft copolymers and a process for their preparation | ROHM & HAAS (US) | 1994-09-28 | — | — | EP | disclosed |
| WO-1994005655-A1 | ANTIPSYCHOTIC QUINOLINE DERIVATIVES OF BENZODIOXANMETHYLAMINE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-03-17 | — | — | WO | disclosed |
| US-5232985-A | Blend of polyamide, polyglut imide and graft polymer of amide-glut | ROHM AND HAAS COMPANY (US) | 1993-08-03 | — | — | US | disclosed |
| US-5084517-A | Polyamides grafted polyglutarimide ionomers for core/shell polymers with impact strength | ROHM AND HAAS COMPANY | 1992-01-28 | — | — | US | disclosed |
| JP-H03115434-A | GRAFT COPOLYMER AND ITS PRODUCTION | ROHM & HAAS CO | 1991-05-16 | — | — | JP | disclosed |
| CN-1049846-A | Glutarimide with weeding activity | ROHM & HAAS (US) | 1991-03-13 | — | — | CN | disclosed |
| EP-0409481-A2 | Graft copolymers and a process for their preparation | ROHM AND HAAS COMPANY (US) | 1991-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544105-B2 | Deoxyuridine triphosphatase inhibitors containing cyclopropano linkage | DPYD, DUT, TYMP | CRBN 3608/4885DDB1 108/4885ALDH1A1 966/4885 |
| US-11174271-B2 | 6-membered uracil isosteres | UNG, DUT, DPYD | CRBN 3184/4885DDB1 80/4885ALDH1A1 972/4885 |
| US-20190270756-A1 | 6-MEMBERED URACIL ISOSTERES | UNG, DUT, DPYD | CRBN 3184/4885DDB1 80/4885ALDH1A1 972/4885 |
| US-20180201586-A1 | DEOXYURIDINE TRIPHOSPHATASE INHIBITORS CONTAINING CYCLOPROPANO LINKAGE | DUT, DPYD, TYMP | CRBN 3374/4885DDB1 88/4885ALDH1A1 1105/4885 |
| US-20140011844-A1 | MIGRASTATIN ANALOGS AND USES THEREOF | KDR, HMGCR, LPAR3 | CRBN 2072/4885DDB1 4207/4885ALDH1A1 1123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.