SCHEMBL2453203

SCHEMBL2453203

CCC(C(=O)O)=C(Cl)C=Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.50
NPC1 O15118 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
GLA P06280 1/20 0.50
HAO1 Q9UJM8 1/20 0.49
ALDH1A1 P00352 3/20 0.48
HDAC3 O15379 3/20 0.48
LMNA P02545 3/20 0.48
HDAC4 P56524 2/20 0.48
HDAC1 Q13547 2/20 0.48
HDAC2 Q92769 2/20 0.48
HDAC8 Q9BY41 2/20 0.48
HDAC6 Q9UBN7 2/20 0.48
PLIN1 O60240 2/20 0.48
MAPT P10636 2/20 0.48
RECQL P46063 2/20 0.48
PLIN5 Q00G26 2/20 0.48
ABHD5 Q8WTS1 2/20 0.48
TNKS O95271 1/20 0.48
HCAR2 Q8TDS4 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10581527 0.81 GLA (0.56) TDP1NPC1L3MBTL1GLAHAO1
SCHEMBL5836506 0.77 TDP1 (0.60) TDP1NPC1L3MBTL1GLAHAO1
SCHEMBL10671139 0.77 GLA (0.55) TDP1NPC1L3MBTL1GLAHAO1
SCHEMBL10671136 0.77 GLA (0.55) TDP1NPC1L3MBTL1GLAHAO1
SCHEMBL8642707 0.75 GLA (0.53) TDP1NPC1L3MBTL1GLAHAO1
SCHEMBL337209 0.75 GLA (0.53) TDP1NPC1L3MBTL1GLAHAO1
SCHEMBL14606209 0.75 TDP1 (0.52) TDP1NPC1L3MBTL1GLAHAO1
SCHEMBL565437 0.74 ALDH1A1 (0.63) TDP1NPC1L3MBTL1GLAHAO1
SCHEMBL18406217 0.74 ALDH1A1 (0.63) TDP1NPC1L3MBTL1GLAHAO1
SCHEMBL565436 0.74 ALDH1A1 (0.63) TDP1NPC1L3MBTL1GLAHAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2059856-B1 ELECTROSTATIC IMAGE DEVELOPING TONER, TWO-COMPONENT DEVELOPER, IMAGE FORMING METHOD AND PROCESS CARTRIDGE RICOH CO LTD (JP) 2016-05-25 EP disclosed
EP-2548081-A1 TONER, DEVELOPER, PROCESS CARTRIDGE, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS Ricoh Company, Ltd. (JP) 2013-01-23 EP disclosed
US-8084179-B2 Electrostatic image developing toner having specific variation coefficient of number distribution, two-component developer, image forming method and process cartridge RICOH COMPANY, LTD. (JP) 2011-12-27 US disclosed
WO-2011115304-A1 TONER, DEVELOPER, PROCESS CARTRIDGE, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2011-09-22 WO disclosed
US-20090202934-A1 ELECTROSTATIC IMAGE DEVELOPING TONER, TWO-COMPONENT DEVELOPER, IMAGE FORMING METHOD AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2009-08-13 US disclosed
EP-2059856-A1 ELECTROSTATIC IMAGE DEVELOPING TONER, TWO-COMPONENT DEVELOPER, IMAGE FORMING METHOD AND PROCESS CARTRIDGE Ricoh Company, Ltd. (JP) 2009-05-20 EP disclosed
US-20080076054-A1 Toner, production method thereof, toner container, developer, image forming apparatus and process cartridge using the same RICOH COMPANY, LTD. (JP) 2008-03-27 US disclosed
WO-2008029863-A1 ELECTROSTATIC IMAGE DEVELOPING TONER, TWO-COMPONENT DEVELOPER, IMAGE FORMING METHOD AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2008-03-13 WO disclosed
US-20030207194-A1 Forming a color image on a support, which color image consists of a plurality of color toners each having a melting point or a softening point; then heating the color image upon application of pressure at a first temperature while the TOMITA KUNIHIKO (JP) 2003-11-06 US disclosed
US-6630276-B2 Does not contaminate image forming members such as chargers, or photoreceptors; polysiloxane coated inorganic particle and cyclic siloxane groups present when analyzed using pyrolysis gas chromatography mass spectroscopy RICOH COMPANY, LTD. (JP) 2003-10-07 US disclosed
US-6623897-B2 Color images with uniform high gloss prepared wherein the surface of the fixing member has a ten-point mean roughness not greater than 20 mu m RICOH COMPANY, LTD. (JP) 2003-09-23 US disclosed
US-20020136973-A1 External additive for electrophotographic toner, method for manufacturing the external additive, electrophotographic toner using the external additive, and image forming apparatus using the electrophotographic toner RICOH COMPANY, LTD. (JP) 2002-09-26 US disclosed
US-20010006583-A1 Image forming method RICOH COMPANY, LTD (JP) 2001-07-05 US disclosed