Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 10/20 | 0.86 |
| ▸ | BCR | P11274 | 7/20 | 0.86 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.86 |
| ▸ | EPHB6 | O15197 | 3/20 | 0.86 |
| ▸ | STK10 | O94804 | 3/20 | 0.86 |
| ▸ | LCK | P06239 | 3/20 | 0.86 |
| ▸ | FYN | P06241 | 3/20 | 0.86 |
| ▸ | YES1 | P07947 | 3/20 | 0.86 |
| ▸ | LYN | P07948 | 3/20 | 0.86 |
| ▸ | RET | P07949 | 3/20 | 0.86 |
| ▸ | HCK | P08631 | 3/20 | 0.86 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.86 |
| ▸ | SRC | P12931 | 3/20 | 0.86 |
| ▸ | BRAF | P15056 | 3/20 | 0.86 |
| ▸ | PHKG2 | P15735 | 3/20 | 0.86 |
| ▸ | NQO2 | P16083 | 3/20 | 0.86 |
| ▸ | EPHA1 | P21709 | 3/20 | 0.86 |
| ▸ | FECH | P22830 | 3/20 | 0.86 |
| ▸ | EPHA2 | P29317 | 3/20 | 0.86 |
| ▸ | EPHA3 | P29320 | 3/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29380618 | 0.92 | ABL1 (1.00) | ABL1BCRMAPK14EPHB6STK10 | |
| SCHEMBL29358745 | 0.92 | ABL1 (1.00) | ABL1BCRMAPK14EPHB6STK10 | |
| SCHEMBL4699731 | 0.92 | ABL1 (1.00) | ABL1BCRMAPK14EPHB6STK10 | |
| SCHEMBL4697866 | 0.91 | BRAF (0.89) | ABL1BCRMAPK14EPHB6STK10 | |
| SCHEMBL24532064 | 0.90 | ABL1 (0.74) | ABL1BCRMAPK14EPHB6STK10 | |
| SCHEMBL24532034 | 0.89 | ABL1 (0.73) | ABL1BCRMAPK14EPHB6STK10 | |
| SCHEMBL24532065 | 0.88 | ABL1 (0.72) | ABL1BCRMAPK14EPHB6STK10 | |
| SCHEMBL24532041 | 0.88 | ABL1 (0.79) | ABL1BCRMAPK14EPHB6STK10 | |
| SCHEMBL24532058 | 0.88 | ABL1 (0.83) | ABL1BCRMAPK14EPHB6STK10 | |
| SCHEMBL24532087 | 0.87 | ABL1 (0.73) | ABL1BCRMAPK14EPHB6STK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240166759-A1 | COMBINATIONS COMPRISING ANTI-TM4SF1 ANTIBODIES AND IMMUNOTHERAPEUTIC AGENTS AND METHODS OF USING THE SAME | ANGIEX, INC. | 2024-05-23 | — | — | US | disclosed |
| US-20220194943-A1 | RECEPTOR TYROSINE KINASE INHIBITORS FOR TREATMENT OF PROTEIN KINASE MODULATION-RESPONSIVE DISEASE OR DISORDER | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (US) | 2022-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220194943-A1 | RECEPTOR TYROSINE KINASE INHIBITORS FOR TREATMENT OF PROTEIN KINASE MODULATION-RESPONSIVE DISEASE OR DISORDER | EPHA1, EPHB2, EPHB1 | ABL1 75/4885BCR 311/4885MAPK14 185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.