Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | F12 | P00748 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31125170 | 0.98 | CYP2A6 (0.48) | CYP2A6ACHEF12PLAUNCF1 | |
| SCHEMBL4067893 | 0.98 | CYP2A6 (0.48) | CYP2A6ACHEF12PLAUNCF1 | |
| Hydrochloric Acid SCHEMBL26126612 | 0.97 | CYP2A6 (0.47) | CYP2A6ACHEF12PLAUNCF1 | |
| Bromide SCHEMBL6680136 | 0.97 | CYP2A6 (0.47) | CYP2A6ACHEF12PLAUNCF1 | |
| Iodide SCHEMBL4729054 | 0.93 | CYP2A6 (0.44) | CYP2A6ACHEF12PLAUNCF1 | |
| SCHEMBL2030595 | 0.93 | CYP2A6 (0.47) | CYP2A6ACHEF12PLAUNCF1 | |
| SCHEMBL6114275 | 0.92 | CYP2A6 (0.46) | CYP2A6ACHEF12PLAUNCF1 | |
| SCHEMBL4058130 | 0.92 | CYP2A6 (0.46) | CYP2A6ACHEF12PLAUNCF1 | |
| SCHEMBL4764703 | 0.92 | CYP2A6 (0.46) | CYP2A6ACHEF12PLAUNCF1 | |
| SCHEMBL3905155 | 0.92 | CYP2A6 (0.46) | CYP2A6ACHEF12PLAUNCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650328-B1 | METHOD FOR FORMING OXIDE FILM ON METAL SURFACE USING IONIC LIQUID, ELECTROLYTIC CAPACITOR AND ELECTROLYTE THEREOF | KANEKA CORP (JP) | 2016-10-19 | — | — | EP | disclosed |
| EP-2540875-A1 | Electrolytic capacitor including ionic liquid in electrolyte | KANEKA CORPORATION (JP) | 2013-01-02 | — | — | EP | disclosed |
| US-8034956-B2 | Ionic liquid and method for producing the same, method for forming oxide film on metal surface, electrolyte capacitor and electrolyte | KANEKA CORPORATION (JP) | 2011-10-11 | — | — | US | disclosed |
| US-8014128-B2 | Method for forming oxide film on metal surface using ionic liquid, electrolytic capacitor and electrolyte thereof | KANEKA CORPORATION (JP) | 2011-09-06 | — | — | US | disclosed |
| US-7746623-B2 | Electrolytic capacitor and electrolyte thereof | KANEKA CORPORATION (JP) | 2010-06-29 | — | — | US | disclosed |
| US-20080304208-A1 | ELECTROLYTIC CAPACITOR AND ELECTROLYTE THEREOF | KANEKA CORPORATION | 2008-12-11 | — | — | US | disclosed |
| US-20070263341-A1 | Ionic Liquid and Method for Producing the Same, Method for Forming Oxide Film on Metal Surface, Electrolytic Capicitor and Electrolyte | KANEKA CORPORATION (JP) | 2007-11-15 | — | — | US | disclosed |
| US-20060181835-A1 | Method for forming oxide film on metal surface using ionic liquid, electrolytic capacitor and electrolyte thereof | KANEKA CORPORATION (JP) | 2006-08-17 | — | — | US | disclosed |
| EP-1650328-A1 | METHOD FOR FORMING OXIDE FILM ON METAL SURFACE USING IONIC LIQUID, ELECTROLYTIC CAPACITOR AND ELECTROLYTE THEREOF | KANEKA CORPORATION (JP) | 2006-04-26 | — | — | EP | disclosed |
| US-4855022-A | Method for the impregnation of electrolytic capacitors with tetracyanoquinodimethane salts | COMPAGNIE EUROPEENNE DE COMPOSANTS ELECTRONIQUES (FR) | 1989-08-08 | — | — | US | disclosed |